SCHEMBL563322

SCHEMBL563322

O=C(O)c1cc(/N=C2\C=CC3=C(C2)Sc2ccccc2N3)cc(C(=O)O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 8/20 0.38
▸ GAA P10253 8/20 0.37
▸ MAPT P10636 7/20 0.37
▸ MEN1 O00255 5/20 0.37
▸ KMT2A Q03164 5/20 0.37
▸ ALOX15 P16050 2/20 0.37
▸ SNCA P37840 2/20 0.37
▸ CYBB P04839 1/20 0.37
▸ APP P05067 1/20 0.37
▸ NOX3 Q9HBY0 1/20 0.37
▸ NOX4 Q9NPH5 1/20 0.37
▸ POLB P06746 4/20 0.36
▸ NPC1 O15118 4/20 0.36
▸ RAB9A P51151 4/20 0.36
▸ KDM4E B2RXH2 3/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.36
▸ MCL1 Q07820 2/20 0.36
▸ NPSR1 Q6W5P4 3/20 0.36
▸ GFER P55789 1/20 0.36
▸ MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436040 1.00 NOX1 (0.38) NOX1GAAMAPTMEN1KMT2A
SCHEMBL436033 0.89 NOX1 (0.41) NOX1GAAMAPTMEN1KMT2A
SCHEMBL563959 0.84 GAA (0.42) NOX1GAAMAPTMEN1KMT2A
SCHEMBL433397 0.79 MAPT (0.41) NOX1GAAMAPTMEN1KMT2A
SCHEMBL433232 0.77 NOX1 (0.42) NOX1GAAMAPTMEN1KMT2A
SCHEMBL10370002 0.76 GAA (0.48) NOX1GAAMAPTMEN1KMT2A
SCHEMBL434952 0.74 SNCA (0.48) NOX1GAAMAPTMEN1KMT2A
SCHEMBL435356 0.74 NOX1 (0.35) NOX1GAAMAPTMEN1KMT2A
SCHEMBL434961 0.74 NOX1 (0.46) NOX1GAAMAPTMEN1KMT2A
SCHEMBL434466 0.74 MAPT (0.46) NOX1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3753481-B1 TRANSIENT DECAY AMPEROMETRY DEVICE ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2024-07-17 — — EP disclosed
EP-2535703-B1 Multi-electrode biosensor system ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-11-03 — — EP disclosed
US-11091790-B2 Determining analyte concentration from variant concentration distribution in measurable species ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-08-17 — — US disclosed
EP-3369825-B1 POROUS PARTICLE REAGENT COMPOSITIONS AND DEVICES FOR BIOSENSORS ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-07-28 — — EP disclosed
US-10989683-B2 Identifying ionizable species with voltammetric duty cycles ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-04-27 — — US disclosed
EP-2499483-B1 Method and biosensor for assessing the volume of a blood sample ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-03-17 — — EP disclosed
US-10947328-B2 Polymer comprising a plurality of phenothiazine groups and methods of making the same ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-03-16 — — US disclosed
US-10895550-B2 Multi-region and potential test sensors, methods, and systems ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-01-19 — — US disclosed
EP-3753481-A1 TRANSIENT DECAY AMPEROMETRY Ascensia Diabetes Care Holdings AG (CH) 2020-12-23 — — EP disclosed
EP-3543348-B1 BIOSENSOR SYSTEM HAVING ENHANCED STABILITY AND HEMATOCRIT PERFORMANCE ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2020-11-18 — — EP disclosed
WO-2010006253-A1 SYSTEMS AND METHODS INCLUDING AMPEROMETRIC AND VOLTAMMETRIC DUTY CYCLES BAYER HEALTHCARE LLC (US) 2010-01-14 — — WO disclosed
EP-2089531-A1 BIOSENSOR SYSTEM HAVING ENHANCED STABILITY AND HEMATOCRIT PERFORMANCE Bayer Healthcare, LLC (US) 2009-08-19 — — EP disclosed
EP-2083674-A2 TRANSIENT DECAY AMPEROMETRY Bayer Healthcare, LLC (US) 2009-08-05 — — EP disclosed
US-20090178936-A1 Porous Particle Reagent Compositions, Devices, and Methods for Biosensors BAYER HEALTHCARE LLC (US) 2009-07-16 — — US disclosed
WO-2009076402-A1 POROUS PARTICLE REAGENT COMPOSITIONS, DEVICES, AND METHODS FOR BIOSENSORS BAYER HEALTHCARE LLC (US) 2009-06-18 — — WO disclosed
WO-2009042631-A2 MULTI-ELECTRODE TEST SENSORS BAYER HEALTHCARE LLC (US) 2009-04-02 — — WO disclosed
US-20090068754-A1 Transient Decay Amperometry BAYER HEALTHCARE LLC (US) 2009-03-12 — — US disclosed
US-20080156662-A1 electrochemical sensor strips; By reducing the amount of mediator and/or enzyme used on the sensor strip, the long-term stability of the reagent composition may be increased in relation to conventional biosensors and reagent compositions BAYER HEALTHCARE LLC (US) 2008-07-03 — — US disclosed
WO-2008051742-A2 TRANSIENT DECAY AMPEROMETRY BAYER HEALTHCARE LLC (US) 2008-05-02 — — WO disclosed
WO-2008036516-A1 BIOSENSOR SYSTEM HAVING ENHANCED STABILITY AND HEMATOCRIT PERFORMANCE BAYER HEALTHCARE LLC (US) 2008-03-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947328-B2 Polymer comprising a plurality of phenothiazine groups and methods of making the same PAH, TYK2, PNMT NOX1 2861/4885GAA 380/4885MAPT 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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