Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075428 | 0.86 | EHMT2 (0.56) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL1479297 | 0.84 | ALDH1A1 (0.55) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL3125142 | 0.83 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL3070731 | 0.83 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL4757038 | 0.83 | EHMT2 (0.52) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL4483430 | 0.79 | ALDH1A1 (0.54) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL31289372 | 0.78 | — | — | |
| SCHEMBL1607377 | 0.78 | LMNA (0.51) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL14524405 | 0.78 | EHMT2 (0.47) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A | |
| SCHEMBL464425 | 0.78 | HPGD (0.49) | EHMT2EHMT1APOBEC3GALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-03-26 | — | — | US | disclosed |
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2020020816-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | WO | disclosed |
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-09-19 | — | — | US | disclosed |
| EP-3519389-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-07 | — | — | EP | disclosed |
| EP-3515907-A1 | NOVEL TRIAZOLE DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| EP-3515906-A1 | NOVEL TRIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20190211002-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-11 | — | — | US | disclosed |
| EP-3334718-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2018060091-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| WO-2018054832-A1 | NOVEL TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018054829-A1 | NOVEL TRIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2017029179-A1 | TRIAZOLE DERIVATIVES, INTERMEDIATES THEREOF AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-23 | — | — | WO | disclosed |
| CN-101638374-A | Oxime compound and resist composition containing the same | SUMITOMO CHEMICAL CO JP | 2010-02-03 | — | — | CN | disclosed |
| US-7161015-B1 | Method of making 2-furylalkylketones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2007-01-09 | — | — | US | disclosed |
| EP-0480939-A1 | HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY. | UPJOHN CO (US) | 1992-04-22 | — | — | EP | disclosed |
| US-4427683-A | Antiinflammatory 2'-pyridyl-1'-oxide carbothiolate and carbodithioate compounds | SDS BIOTECH CORPORATION (US) | 1984-01-24 | — | — | US | disclosed |
| EP-0089661-A1 | Antiinflammatory 2'-pyridyl-1'-oxide carbothiolate and carbodithioate compounds | SDS BIOTECH CORPORATION (US) | 1983-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190281828-A1 | NOVEL TRIAZOLE DERIVATIVES | CBR3, TH, PADI1 | EHMT2 1528/4885EHMT1 1155/4885APOBEC3G 1143/4885 |
| US-20200045967-A1 | NOVEL TRIAZOLE DERIVATIVES | CYP51A1, ERG28, SBK3 | EHMT2 3110/4885EHMT1 2819/4885APOBEC3G 1824/4885 |
| US-20190211002-A1 | NOVEL TRIAZOLE DERIVATIVES | ERG28, CYP51A1, SBK3 | EHMT2 2484/4885EHMT1 2067/4885APOBEC3G 1163/4885 |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | IPMK, PIP5K1B, PIP5K1C | EHMT2 682/4885EHMT1 569/4885APOBEC3G 2090/4885 |
| US-20200095223-A1 | NOVEL TRIAZOLETHIONE DERIVATIVES | CYP51A1, SBK3, TST | EHMT2 2788/4885EHMT1 2076/4885APOBEC3G 3154/4885 |
| US-20200029563-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES | PIP5K1B, PIP5K1A, PIP5K1C | EHMT2 1911/4885EHMT1 1578/4885APOBEC3G 2841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.