SCHEMBL563737

SCHEMBL563737

CC(C)(C)c1ccccc1C#Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.50
CYP1A2 P05177 3/20 0.50
CYP3A4 P08684 3/20 0.50
CYP2C9 P11712 3/20 0.50
HPGD P15428 3/20 0.50
CYP2C19 P33261 3/20 0.50
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
APP P05067 1/20 0.50
CA2 P00918 3/20 0.47
CA12 O43570 2/20 0.47
CA9 Q16790 2/20 0.47
RAB9A P51151 3/20 0.43
FFAR1 O14842 1/20 0.42
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28564278 0.85 NPC1 (0.44) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL5502533 0.85 FFAR1 (0.38) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL28995058 0.84 MAPT (0.47) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL563999 0.79 FFAR1 (0.60) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL2114742 0.77 APP (0.75) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL5871989 0.77 APP (0.75) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL6040818 0.76 CA12 (0.41) NPC1ALDH1A1MAPTMEN1CYP1A2
SCHEMBL22911528 0.74 LTA4H (0.48) ALDH1A1HPGDKDM4ETSHRTP53
SCHEMBL8960256 0.73 ALDH1A1 (0.41) ALDH1A1MAPTMEN1CYP1A2CYP3A4
SCHEMBL717061 0.73 ALDH1A1 (0.46) ALDH1A1MAPTCYP1A2CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3223328-B1 ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF KOLON INC (KR) 2020-07-29 EP claimed
EP-3223328-A1 ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF Kolon Industries, Inc. (KR) 2017-09-27 EP claimed
WO-2013100284-A1 METHOD FOR MANUFACTURING ORGANIC SOLAR CELL AND THE ORGANIC SOLAR CELL MANUFACTURING BY USING THE SAME KOLON INDUSTRIES, INC. (KR) 2013-07-04 WO claimed
US-8216686-B2 Conjugated dendron having no heteroatoms is coupled to the triphenylamine core; organic memory device includes an organic active layer between a first electrode and a second electrode, wherein the organic active layer includes the dendrimer; may be used as a nonvolatile memory SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-07-10 US claimed
US-8124238-B2 Redox system ; dendrimer is connected to core by linker group SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-02-28 US claimed
US-8044387-B1 Semiconductor device built on plastic substrate SPANSION LLC (US) 2011-10-25 US claimed
US-8012673-B1 Processing a copolymer to form a polymer memory cell SPANSION LLC (US) 2011-09-06 US claimed
US-7635859-B2 Memory device including dendrimer SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-12-22 US claimed
US-7632706-B2 System and method for processing an organic memory cell SPANSION LLC (US) 2009-12-15 US claimed
US-7608855-B2 Polymer dielectrics for memory element array interconnect SPANSION LLC (US) 2009-10-27 US claimed
EP-1679720-A2 Memory device including dendrimer Samsung Electronics Co., Ltd (KR) 2006-07-12 EP claimed
US-7026702-B2 Memory device ADVANCED MICRO DEVICES, INC. (US) 2006-04-11 US claimed
WO-2005104188-A2 POLYMER DIELECTRICS FOR MEMORY ELEMENT ARRAY INTERCONNECT ADVANCED MICRO DEVICES, INC. (US) 2005-11-03 WO claimed
US-20050224922-A1 Polymer dielectrics for memory element array interconnect MORGAN STANLEY SENIOR FUNDING, INC. 2005-10-13 US claimed
US-6893895-B1 CuS formation by anodic sulfide passivation of copper surface ADVANCED MICRO DEVICES, INC. (US) 2005-05-17 US claimed
US-20040159835-A1 Memory device CYPRESS SEMICONDUCTOR CORPORATION 2004-08-19 US claimed
US-6768157-B2 Memory device ADVANCED MICRO DEVICES, INC. 2004-07-27 US claimed
US-20040026729-A9 Memory device COATUE CORPORATION 2004-02-12 US claimed
US-20030178667-A1 Memory device CYPRESS SEMICONDUCTOR CORPORATION 2003-09-25 US claimed
US-20030155602-A1 Memory device COATUE CORPORATION 2003-08-21 US claimed