Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949662 | 0.78 | CHRNA4 (0.39) | SMN1; SMN2CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL22655057 | 0.78 | IL1B (0.46) | SMN1; SMN2CHRNB2CHRNA4MAPTALDH1A1 | |
| SCHEMBL23148685 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL28670107 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL29637301 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL29685778 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL16705085 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL19664476 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1MAPTCYP1A2ALDH1A1 | |
| SCHEMBL3063761 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNA4MAPTALDH1A1GAA | |
| SCHEMBL2492398 | 0.74 | HTT (0.45) | SMN1; SMN2CHRNB2CHRNA4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103464-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2026-04-16 | — | — | US | disclosed |
| US-12435083-B2 | Cyclopropyl-(hetero)aryl-substituted ethylsulphonyl-pyridine derivatives | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
| WO-2023036934-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYLPYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-03-16 | — | — | WO | disclosed |
| US-7179806-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179806-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| US-7179806-B2 | Δ1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2007-02-20 | — | — | US | disclosed |
| EP-1347957-B1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-20040082586-A1 | Delta 1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1347957-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | Bayer CropScience AG (DE) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002046151-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CYCS, CYP2E1, AHR | SMN1; SMN2 4334/4885L3MBTL1 2181/4885CHRNB2 3006/4885 |
| US-12435083-B2 | Cyclopropyl-(hetero)aryl-substituted ethylsulphonyl-pyridine derivatives | CYCS, CYP2E1, CYP1A1 | SMN1; SMN2 4257/4885L3MBTL1 1985/4885CHRNB2 3027/4885 |
| US-20040082586-A1 | Delta 1-pyrrolines used as pesticides | DDT, CHRM1, PRMT1 | SMN1; SMN2 1915/4885L3MBTL1 572/4885CHRNB2 447/4885 |
| US-20260103464-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CBR3, CYCS, CBR1 | SMN1; SMN2 3977/4885L3MBTL1 211/4885CHRNB2 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.