Sugi Predict

Sugi Predict / Compounds / SCHEMBL564660

SCHEMBL564660

SCHEMBL564660

C=CCNc1ccc(-c2cccc(Oc3cccc(-c4ccc(NCC=C)c(O)c4)c3)c2)cc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 4/20 0.36
▸ FFAR1 O14842 2/20 0.36
▸ APP P05067 1/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ GLA P06280 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ GABRA1 P14867 1/20 0.34
▸ GABRB2 P47870 1/20 0.34
▸ XDH P47989 3/20 0.34
▸ SLC22A12 Q96S37 3/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565803 0.87 GAA (0.37) RAB9AGLAGAAHTTSMN1; SMN2
SCHEMBL565622 0.85 GABRA1 (0.44) APPRAB9AGAAHTTSMN1; SMN2
SCHEMBL564768 0.84 HSD17B1 (0.47) APPGABRA1GABRB2
SCHEMBL565603 0.83 GAA (0.48) RAB9AGLAGAAHTTSMN1; SMN2
SCHEMBL566053 0.82 HTT (0.36) FFAR1RAB9AGLAGAAHTT
SCHEMBL564675 0.81 GABRA1 (0.37) APPRAB9AGAAHTTGABRA1
SCHEMBL565092 0.79 ALOX5 (0.46) RAB9AGAAGABRA1GABRB2KDM4E
Ether SCHEMBL564659 0.79 HSD17B1 (0.39) —
Ether SCHEMBL564674 0.78 MAPT (0.39) RAB9AGAAHTTSMN1; SMN2GABRA1
SCHEMBL566192 0.77 CA12 (0.43) FFAR1RAB9AGLAGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 — — US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 — — US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 — — US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 — — US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 — — US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 FFAR4 2160/4885FFAR1 533/4885APP 3833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.