SCHEMBL565803

SCHEMBL565803

C=CCNc1ccc(-c2ccc(Oc3ccc(-c4ccc(NCC=C)c(O)c4)cc3)cc2)cc1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
GLA P06280 1/20 0.37
HTT P42858 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
MAPT P10636 3/20 0.36
NPC1 O15118 2/20 0.36
POLB P06746 1/20 0.36
HCAR3 P49019 1/20 0.35
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 1/20 0.32
KIF11 P52732 1/20 0.32
TGM2 P21980 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565622 0.89 GABRA1 (0.44) GAARAB9ASMN1; SMN2HTTGABRA1
SCHEMBL565885 0.88 GABRA1 (0.40) GAARAB9ASMN1; SMN2GLAHTT
SCHEMBL564660 0.87 FFAR4 (0.36) GAARAB9ASMN1; SMN2GLAHTT
SCHEMBL565092 0.86 ALOX5 (0.46) GAARAB9AGABRA1GABRB2MAPT
SCHEMBL564675 0.85 GABRA1 (0.37) GAARAB9AHTTGABRA1GABRB2
SCHEMBL565603 0.84 GAA (0.48) GAARAB9ASMN1; SMN2GLAHTT
SCHEMBL566192 0.84 CA12 (0.43) GAARAB9ASMN1; SMN2GLAHTT
Ether SCHEMBL564674 0.82 MAPT (0.39) GAARAB9ASMN1; SMN2HTTGABRA1
Ether SCHEMBL565802 0.80 ALOX5 (0.38) GAARAB9ASMN1; SMN2GABRA1GABRB2
SCHEMBL564768 0.79 HSD17B1 (0.47) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 GAA 3993/4885RAB9A 4688/4885SMN1; SMN2 3254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.