Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS known ✓ | P14324 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.83 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.33 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | INPP5B | P32019 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ITPR3 | Q14573 | 3/20 | 0.32 |
| ▸ | ITPR2 | Q14571 | 1/20 | 0.32 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL2468090 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL15874600 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL15421398 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL1872635 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL5195977 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL1701118 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL334145 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL565146 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL22749766 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 | |
| Pyrophosphoric Acid SCHEMBL7153369 | 1.00 | FDPS (0.83) | FDPSBLMTDP1CA4INPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173568-B | Trisodium pyrophosphate anhydride and preparation method and application thereof | 云南莱德福科技有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-113173568-A | Trisodium monohydrogen pyrophosphate anhydride and preparation method and application thereof | 云南莱德福科技有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-103221031-B | Oral compositions comprising zinc compounds and antimicrobial agents | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2016-04-27 | — | — | CN | claimed |
| US-9044466-B2 | Oral compositions comprising a zinc compound and an anti-microbial agent | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-06-02 | — | — | US | claimed |
| CN-103221031-A | Oral compositions comprising zinc compounds and antimicrobial agents | UNIV NEW YORK STATE RES FOUND | 2013-07-24 | — | — | CN | claimed |
| EP-2600833-A2 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND AND AN ANTI-MICROBIAL AGENT | The Research Foundation for The State University of New York (US) | 2013-06-12 | — | — | EP | claimed |
| WO-2012021415-A2 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND AND AN ANTI-MICROBIAL AGENT | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-02-16 | — | — | WO | claimed |
| US-20120034280-A1 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND AND AN ANTI-MICROBIAL AGENT | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-02-09 | — | — | US | claimed |
| US-12318463-B2 | Compositions and methods for treating canker sores | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-06-03 | — | — | US | disclosed |
| EP-3810067-B1 | METHODS OF INHIBITING MICROBIAL INFECTIONS USING ZINC-CONTAINING COMPOSITIONS | TRIUMPH PHARMACEUTICALS INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20250049659-A1 | ORAL COMPOSITIONS AND METHODS OF REDUCING ORAL MALODOR | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2025-02-13 | — | — | US | disclosed |
| US-12053485-B2 | Methods of inhibiting microbial infections using zinc-containing compositions | TRIUMPH PHARMACEUTICALS INC. (US) | 2024-08-06 | — | — | US | disclosed |
| EP-3760219-B1 | PHARMACEUTICAL COMPOSITION, PACKAGE AND METHOD FOR MANUFACTURING SAME, COMPRISING LYOPHILIZED CHONDROITINASE ABC | SEIKAGAKU KOGYO CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| CN-117222326-A | Novel palatability enhancing compositions | 特种宠物食品公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2012021419-A2 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021415-A2 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND AND AN ANTI-MICROBIAL AGENT | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-02-16 | — | — | WO | disclosed |
| US-20120034280-A1 | ORAL COMPOSITIONS COMPRISING A ZINC COMPOUND AND AN ANTI-MICROBIAL AGENT | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-02-09 | — | — | US | disclosed |
| US-6444134-B1 | SOLVENT, ETCHING, RINSING, FINISHING | THE FLECTO COMPANY, INC. | 2002-09-03 | — | — | US | disclosed |
| US-5880076-A | PERSONAL PRODUCT OR DETERGENT COMPOSITION COMPRISING CYCLIC GLYCACARBAMATE AND/OR GLYCAUREA, SURFACTANT | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5624906-A | Oral hygiene compositions comprising heteroatom containing alkyl aldonamide compounds | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-04-29 | — | — | US | disclosed |