Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387468 | 0.79 | HIF1A (0.36) | ALDH1A1KDM4EHIF1AEIF4A1ACHE | |
| SCHEMBL1387238 | 0.78 | HIF1A (0.34) | RAB9AGAAALDH1A1KDM4EHIF1A | |
| SCHEMBL1333813 | 0.78 | HIF1A (0.34) | ALDH1A1KDM4EHIF1AEIF4A1ACHE | |
| SCHEMBL5667048 | 0.78 | MAPT (0.40) | RAB9AGAAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8978547 | 0.77 | RAB9A (0.39) | RAB9ATDP1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL8727667 | 0.77 | GABRA1 (0.34) | RAB9ATDP1GAAALDH1A1KDM4E | |
| SCHEMBL5646759 | 0.76 | RAB9A (0.38) | RAB9ATDP1ALDH1A1KDM4EGABRA1 | |
| SCHEMBL5644893 | 0.76 | HIF1A (0.35) | RAB9AGAAALDH1A1KDM4EHIF1A | |
| SCHEMBL1387201 | 0.75 | POLB (0.40) | TDP1ALDH1A1KDM4EHIF1AMEN1 | |
| SCHEMBL5646592 | 0.74 | RAB9A (0.34) | RAB9ATDP1GAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | claimed |
| EP-0805993-A4 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0805993-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1997-11-12 | — | — | EP | claimed |
| WO-1997020239-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1997-06-05 | — | — | WO | claimed |
| US-5578252-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1996-11-26 | — | — | US | claimed |
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |
| EP-0805993-A4 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0805993-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997020239-A1 | PHOTOCHROMIC SUBSTITUTED NAPHTHOPYRAN COMPOUNDS | PPG INDUSTRIES, INC. (US) | 1997-06-05 | — | — | WO | disclosed |
| US-5578252-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1996-11-26 | — | — | US | disclosed |