Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445339 | 0.80 | BACE1 (0.40) | RAB9AKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL5181767 | 0.79 | NPSR1 (0.35) | POLBKDM4EALDH1A1GAAMAPT | |
| SCHEMBL9087241 | 0.78 | GSK3B (0.35) | RAB9AKDM4EALDH1A1GAAMAPT | |
| SCHEMBL5650291 | 0.77 | RAB9A (0.39) | GABRA1GABRB2POLBRAB9ATDP1 | |
| SCHEMBL8978547 | 0.76 | RAB9A (0.39) | GABRA1GABRB2RAB9ATDP1ALDH1A1 | |
| SCHEMBL5646759 | 0.76 | RAB9A (0.38) | GABRA1GABRB2RAB9ATDP1KDM4E | |
| SCHEMBL8978536 | 0.75 | ALDH1A1 (0.36) | RAB9ATDP1KDM4EALDH1A1GAA | |
| SCHEMBL7553115 | 0.75 | PDE4D (0.39) | TDP1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL5646592 | 0.74 | RAB9A (0.34) | RAB9ATDP1KDM4EALDH1A1GAA | |
| SCHEMBL5648211 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744070-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1998-04-28 | — | — | US | disclosed |