Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EIF4A1 | P60842 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5648211 | 0.88 | — | — | |
| SCHEMBL29565467 | 0.88 | — | — | |
| SCHEMBL8978547 | 0.85 | RAB9A (0.39) | RAB9AEIF4A1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL5646759 | 0.85 | RAB9A (0.38) | RAB9AEIF4A1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL5643452 | 0.84 | SMN1; SMN2 (0.38) | RAB9AALDH1A1KDM4E | |
| SCHEMBL7787523 | 0.82 | RAB9A (0.34) | RAB9AEIF4A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL6131950 | 0.80 | L3MBTL1 (0.41) | EIF4A1ALDH1A1CYP3A4TSHRCYP2C19 | |
| SCHEMBL8978536 | 0.79 | ALDH1A1 (0.36) | RAB9AALDH1A1TDP1KDM4EGAA | |
| SCHEMBL6169985 | 0.79 | L3MBTL1 (0.43) | RAB9AEIF4A1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL5648078 | 0.78 | SIGMAR1 (0.32) | RAB9AEIF4A1ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | claimed |
| EP-0801750-B1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG IND OHIO INC (US) | 2001-11-07 | — | — | EP | claimed |
| EP-0801750-A4 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES INC (US) | 1997-12-10 | — | — | EP | claimed |
| EP-0801750-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1997-10-22 | — | — | EP | claimed |
| US-7166357-B2 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040185268-A1 | Photochromic articles that activate behind ultraviolet radiation blocking transparencies and methods for preparation | TRANSITIONS OPTICAL LIMITED (IE) | 2004-09-23 | — | — | US | disclosed |
| EP-0801750-B1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG IND OHIO INC (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0801750-A4 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0801750-A1 | NOVEL SUBSTITUTED PHENANTHROPYRANS | PPG INDUSTRIES, INC. (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5514817-A | PHOTOCHROMIC | PPG INDUSTRIES, INC. (US) | 1996-05-07 | — | — | US | disclosed |