Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646759 | 0.91 | RAB9A (0.38) | RAB9AGABRA1GABRB2ACHETDP1 | |
| SCHEMBL5646592 | 0.85 | RAB9A (0.34) | RAB9ATDP1EIF4A1CYP3A4CYP2C19 | |
| SCHEMBL1408896 | 0.85 | ATM (0.41) | RAB9ATDP1HTTTP53ATM | |
| SCHEMBL29565080 | 0.85 | ATM (0.41) | RAB9ATDP1HTTTP53ATM | |
| SCHEMBL8978536 | 0.85 | ALDH1A1 (0.36) | RAB9ATDP1TP53L3MBTL1ALDH1A1 | |
| SCHEMBL8978509 | 0.84 | L3MBTL1 (0.40) | RAB9ATDP1HTTTP53ATM | |
| SCHEMBL29565483 | 0.84 | L3MBTL1 (0.40) | RAB9ATDP1HTTTP53ATM | |
| SCHEMBL5645434 | 0.79 | L3MBTL1 (0.38) | ACHETDP1HTTTP53ATM | |
| SCHEMBL6652780 | 0.79 | ALDH1A1 (0.34) | TDP1TP53ALDH1A1 | |
| SCHEMBL5644282 | 0.78 | ALDH1A1 (0.39) | RAB9AHTTL3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573712-A | PHOTOCHROMIC ARTICLE COMPRISING ORGANIC HOST AND THE PHOTOCHROMIC NAPHTHOPYRAN | TRANSITIONS OPTICAL, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |