Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653132 | 1.00 | KDM4E (0.55) | KDM4EHTTHSD17B3MEN1TP53 | |
| SCHEMBL3249800 | 0.87 | KDM4E (0.47) | KDM4EHTTHSD17B3MAPTLMNA | |
| SCHEMBL27980958 | 0.80 | ALDH1A1 (0.49) | KDM4EHTTMEN1MAPTTSHR | |
| SCHEMBL70058 | 0.75 | TYR (0.51) | KDM4EHTTMEN1TP53CYP3A4 | |
| SCHEMBL7855809 | 0.74 | HTT (0.50) | KDM4EHTTHSD17B3MEN1TP53 | |
| SCHEMBL31544881 | 0.73 | TYR (0.53) | KDM4EHTTMEN1TP53CYP3A4 | |
| SCHEMBL7599990 | 0.73 | P2RX7 (0.48) | ALDH1A1 | |
| SCHEMBL29429345 | 0.72 | TYR (0.55) | MEN1CYP3A4ALOX5MAPTTYR | |
| SCHEMBL490490 | 0.72 | TYR (0.55) | MEN1CYP3A4ALOX5MAPTTYR | |
| SCHEMBL3654494 | 0.72 | HTT (0.97) | KDM4EHTTHSD17B3MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109364-B2 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA | 2006-09-19 | — | — | US | disclosed |
| US-20040034242-A1 | Group of anti-cancer compounds with specific structure and their production method | YANG ZHENHUA (US) | 2004-02-19 | — | — | US | disclosed |