Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | SDCBP | O00560 | 3/20 | 0.55 |
| ▸ | SDC2 | P34741 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662816 | 0.92 | THRB (0.54) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL120182 | 0.85 | ALOX15 (0.57) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL24834797 | 0.82 | SDCBP (0.55) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL23867096 | 0.82 | SDCBP (0.55) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL22997450 | 0.82 | SDCBP (0.55) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL30856522 | 0.81 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2013546 | 0.81 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL311675 | 0.81 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL15338689 | 0.81 | ALOX15 (0.57) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL31667158 | 0.81 | NPC1 (0.54) | ALOX15KDM4EALDH1A1TSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166617-B2 | Cyclic amide derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030212094-A1 | Novel cyclic amide derivatives | MITSUBISHI PHARMA CORPORATION (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-1260512-A1 | NOVEL CYCLIC AMIDE DERIVATIVES | Mitsubishi Pharma Corporation (JP) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212094-A1 | Novel cyclic amide derivatives | SIGMAR1, OPRM1, OPRD1 | ALOX15 1648/4885KDM4E 2058/4885ALDH1A1 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.