Ether

Ether

SCHEMBL565884

C=CCNc1cc(-c2ccc(O)cc2)ccc1O.CCOCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
GABRA1 P14867 3/20 0.36
GABRB2 P47870 3/20 0.36
ESR1 P03372 3/20 0.36
ESR2 Q92731 3/20 0.36
PELI1 Q96FA3 1/20 0.35
KDM4E B2RXH2 2/20 0.35
APOBEC3A P31941 1/20 0.35
GFER P55789 1/20 0.35
HDAC1 Q13547 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
MGLL Q99685 7/20 0.34
GAA P10253 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B1 P14061 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL565588 0.94 GABRA1 (0.40) ALOX5GABRA1GABRB2KDM4EAPOBEC3A
SCHEMBL564433 0.90 ALOX5 (0.46) ALOX5GABRA1GABRB2ESR1ESR2
Ether SCHEMBL565802 0.89 ALOX5 (0.38) ALOX5GABRA1GABRB2ESR1ESR2
SCHEMBL566048 0.84 GABRA1 (0.48) ALOX5GABRA1GABRB2KDM4EAPOBEC3A
Ether SCHEMBL564674 0.83 MAPT (0.39) GABRA1GABRB2KDM4EGAALMNA
SCHEMBL565885 0.80 GABRA1 (0.40) GABRA1GABRB2KDM4EAPOBEC3AGFER
SCHEMBL565092 0.78 ALOX5 (0.46) ALOX5GABRA1GABRB2ESR1ESR2
SCHEMBL10588568 0.77 GAA (0.44) GABRA1GABRB2KDM4EGAALMNA
SCHEMBL565445 0.77 HSD17B1 (0.47) GABRA1GABRB2ESR1ESR2PELI1
SCHEMBL565589 0.77 GABRA1 (0.40) ALOX5GABRA1GABRB2KDM4EAPOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ALOX5 1446/4885GABRA1 1019/4885GABRB2 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.