Ether

Ether

SCHEMBL565802

C=CCNc1ccc(-c2ccc(O)cc2)cc1O.CCOCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
ESR1 P03372 4/20 0.33
ESR2 Q92731 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
HCAR3 P49019 1/20 0.33
PELI1 Q96FA3 1/20 0.33
HSD17B1 P14061 1/20 0.33
GAA P10253 3/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CREBBP Q92793 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL564674 0.94 MAPT (0.39) NPC1POLBMAPTRAB9AGABRA1
SCHEMBL565092 0.90 ALOX5 (0.46) ALOX5NPC1POLBMAPTRAB9A
Ether SCHEMBL565884 0.89 ALOX5 (0.38) ALOX5MAPTESR1ESR2GABRA1
SCHEMBL565622 0.84 GABRA1 (0.44) ALOX5NPC1POLBMAPTRAB9A
Ether SCHEMBL565588 0.83 GABRA1 (0.40) ALOX5NPC1MAPTRAB9AGABRA1
SCHEMBL565803 0.80 GAA (0.37) ALOX5NPC1POLBMAPTRAB9A
SCHEMBL564433 0.78 ALOX5 (0.46) ALOX5MAPTESR1ESR2GABRA1
SCHEMBL9240095 0.77 KDM4E (0.41) MAPTHCAR3GAALMNATSHR
SCHEMBL564675 0.77 GABRA1 (0.37) NPC1POLBMAPTRAB9AGABRA1
SCHEMBL564768 0.77 HSD17B1 (0.47) ESR1ESR2GABRA1GABRB2PELI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 ALOX5 1446/4885NPC1 2373/4885POLB 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.