Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 16/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30628893 | 1.00 | MRGPRX4 (0.67) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL20795336 | 0.87 | MRGPRX4 (0.51) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL27905651 | 0.86 | MRGPRX4 (0.54) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL22681476 | 0.86 | ATM (0.57) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL3149977 | 0.85 | MAOB (0.57) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL28277763 | 0.85 | MRGPRX4 (0.58) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| Benzoic Acid SCHEMBL29002939 | 0.85 | NR4A2 (0.59) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL6000790 | 0.85 | MRGPRX4 (0.68) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL45113 | 0.84 | MRGPRX4 (0.57) | MRGPRX4TP53PKMNFKB1NFKB2 | |
| SCHEMBL2824632 | 0.84 | PARP1 (0.56) | MRGPRX4TP53PKMNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118006054-B | Weather-resistant and anti-fouling plastic wallboard and preparation method thereof | 浙江奕科新材料股份有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118006054-A | Weather-resistant and anti-fouling plastic wallboard and preparation method thereof | 浙江奕科新材料股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | claimed |
| EP-1399431-B1 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-02-18 | — | — | EP | claimed |
| US-6982263-B2 | Nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | claimed |
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-26 | — | — | US | claimed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| CN-118006054-B | Weather-resistant and anti-fouling plastic wallboard and preparation method thereof | 浙江奕科新材料股份有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118006054-A | Weather-resistant and anti-fouling plastic wallboard and preparation method thereof | 浙江奕科新材料股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | disclosed |
| CN-110183371-B | Preparation process of zafirlukast intermediate | 南京医科大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-110183371-B | Preparation process of zafirlukast intermediate | 南京医科大学 | 2022-06-14 | — | — | CN | disclosed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-0107693-B1 | 2,3,4-TRINOR-1,5-INTER-M-PHENYLENE-PROSTACYCLIN-I2 ANALOGUES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-07-27 | — | — | EP | disclosed |
| US-4638002-A | ANTIAGGLOMERANTS, HYPOTENSIVE, ANTISECRETORY, ANTISPASMODIC, ANTIULCER, BRONCHODILATOR, ANTIHISTAMINES | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1987-01-20 | — | — | US | disclosed |
| EP-0107693-A4 | 2,3,4-TRINOR-1,5-INTER-M-PHENYLENE-PROSTACYCLIN-I2 ANALOGUES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1984-09-17 | — | — | EP | disclosed |
| EP-0107693-A1 | 2,3,4-TRINOR-1,5-INTER-M-PHENYLENE-PROSTACYCLIN-I2 ANALOGUES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1984-05-09 | — | — | EP | disclosed |
| WO-1983004021-A1 | 2,3,4-TRINOR-1,5-INTER-M-PHENYLENE-PROSTACYCLINE-I2 ANALOGUES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1983-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | MRGPRX4 66/4885TP53 503/4885PKM 2004/4885 |
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | NOS1, CTSK, CTSS | MRGPRX4 821/4885TP53 2785/4885PKM 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.