Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660770 | 0.99 | KMT2A (0.54) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5659402 | 0.78 | KCNJ6 (0.45) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14112024 | 0.73 | KMT2A (0.77) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7515503 | 0.72 | KMT2A (0.80) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5658844 | 0.71 | CXCR1 (0.53) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5657166 | 0.71 | HCAR3 (0.40) | KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL841376 | 0.70 | HCAR3 (0.45) | KMT2AALDH1A1HSD17B10HCAR3 | |
| SCHEMBL9043946 | 0.69 | LMNA (0.74) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5658255 | 0.69 | KMT2A (0.61) | KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL19538657 | 0.68 | KMT2A (0.72) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |