Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL29015126 | 0.97 | — | — | |
| SCHEMBL4208 | 0.97 | — | — | |
| SCHEMBL5364993 | 0.97 | LMNA (0.44) | — | |
| SCHEMBL282891 | 0.97 | — | — | |
| SCHEMBL282885 | 0.97 | — | — | |
| Bromide SCHEMBL28709473 | 0.95 | LMNA (0.40) | — | |
| SCHEMBL23701645 | 0.95 | — | — | |
| SCHEMBL2592649 | 0.95 | — | — | |
| SCHEMBL31235672 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL22497834 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350434-B | Process synthesis method for cleavable linker Ala-Ala-Ala | 苏州共康医药科技有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119350434-A | Process synthesis method for cleavable linker Ala-Ala-Ala | 苏州共康医药科技有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-115215853-A | Preparation method of compound serving as farnesoid X receptor agonist | 四川科伦博泰生物医药股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-111517920-B | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2022-04-12 | — | — | CN | claimed |
| CN-113461644-A | Method for recovering tetrahydrofuran from waste solvent | 江苏盈天化学有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-111517920-A | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2020-08-11 | — | — | CN | claimed |
| CN-108912090-B | Test strip for rapidly detecting total amount of alternariol and alternariol monomethyl ether | 北京农业质量标准与检测技术研究中心 | 2020-07-10 | — | — | CN | claimed |
| CN-109232482-A | A kind of economic benefits and social benefits are thermally integrated abstraction distillation separation of tetrahydrofuran-methanol-water azeotropic mixture method | 重庆大学 | 2019-01-18 | — | — | CN | claimed |
| CN-108912090-A | A kind of test strips of quick detection alternariol and alternariol monomethyl ether total amount | 北京农业质量标准与检测技术研究中心 | 2018-11-30 | — | — | CN | claimed |
| CN-105968073-B | The method of tetrahydrofuran in single column extracting rectifying recycling tetrahydrofuran-methanol-water | 青岛科技大学 | 2018-05-29 | — | — | CN | claimed |
| CN-205893131-U | Is tetrahydrofuran retrieved in extraction rectification methyl alcohol single tower system of aquatic tetrahydrofuran | 青岛科技大学 | 2017-01-18 | — | — | CN | claimed |
| CN-105968073-A | Method for recycling tetrahydrofuran in tetrahydrofuran-methanol-water by single-tower extractive distillation | 青岛科技大学 | 2016-09-28 | — | — | CN | claimed |
| CN-103012332-B | Use the method for packing tower distillation separation of tetrahydrofuran-methanol-water solvent slop | JIANGSU ALPHA PHARMACEUTICAL CO., LTD. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-101647829-B | Quality control method of ginkgolide injection | JIANGSU KANION PHARMACEUTICAL | 2014-01-15 | — | — | CN | claimed |
| CN-103012332-A | Method for separating waste solvent of tetrahydrofuran-methanol-water through rectification with packed tower | ALPHA PHARMACEUTICAL CO LTD JIANGSU PROVINCE | 2013-04-03 | — | — | CN | claimed |
| CN-101647830-B | Quality control method of ginkgolide medicinal preparation | JIANGSU KANION PHARMACEUTICAL | 2012-05-23 | — | — | CN | claimed |
| CN-101647830-A | Quality control method of ginkgolide medicinal preparation | JIANGSU KANION PHARMACEUTICAL | 2010-02-17 | — | — | CN | claimed |
| CN-101647829-A | A quality control method of ginkgolide injection | JIANGSU KANION PHARMACEUTICAL | 2010-02-17 | — | — | CN | claimed |
| EP-0248916-A1 | Method for separation of 3S,7R-3,4,5,6,7,8,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one from its 3S,7S-diastereomer | C.R.C. Compagnia di Ricerca Chimica S.p.A. (IT) | 1987-12-16 | — | — | EP | claimed |
| WO-2025134136-A1 | A COMPOUND, A PROBE, AND METHODS THEREOF | L’OREAL (FR) | 2025-06-26 | — | — | WO | disclosed |
| US-20250197420-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2025-06-19 | — | — | US | disclosed |
| EP-4561575-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120053426-A | Bilobalide composition and application thereof in preparation of medicine for preventing and/or treating hemolytic jaundice | 山东新时代药业有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-120000666-A | Spirolactone composition for treating alopecia and preparation method and application thereof | 上海康佰特医药科技发展有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119350434-B | Process synthesis method for cleavable linker Ala-Ala-Ala | 苏州共康医药科技有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119859155-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119350434-A | Process synthesis method for cleavable linker Ala-Ala-Ala | 苏州共康医药科技有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-118440095-A | Preparation method of GnRH receptor antagonist Linzagolix | 中国药科大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-110746376-B | Benzisoselenazolone amine compound and preparation method and application thereof | 上海星叶医药科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117800898-A | Carbazole compound and application thereof | 中国药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-112457366-B | Parallel ring compound as protein degradation agent and preparation method and application thereof | 江西济民可信集团有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| CN-116509812-B | Nicorandil gastric floating sustained-release tablet and preparation method thereof | 江苏诺和必拓新药研发有限公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2024026486-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-117384167-A | Dihydropyrimidine [4,5-d ] pyrimidine-2 (H) -ketone Nrf2 activator and preparation method and application thereof | 寒武智元(南京)生物医药科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-116359394-B | High performance liquid chromatography for separating and detecting related substances in nicorandil tablets | 本溪匠成医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-3594211-B1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116925011-A | Method for recovering tetrahydrofuran and methanol in tetrahydrofuran-containing pharmaceutical wastewater by using reactive extraction distillation bulkhead tower | 青岛科技大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-116509812-A | Nicorandil gastric floating sustained-release tablet and preparation method thereof | 江苏诺和必拓新药研发有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116359394-A | High performance liquid chromatography for separating and detecting related substances in nicorandil tablets | 本溪匠成医药科技有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-114316105-B | Method for removing coating film in PVC (polyvinyl chloride) by suspension method | 宜宾海丰和锐有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| CN-114002352-B | Separation and detection method of folic acid and optical isomer thereof | 四川汇宇制药股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-114685437-B | Eutectic crystal of axitinib and saccharin | 鲁南制药集团股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| US-20220387413-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2022-12-08 | — | — | US | disclosed |
| CN-115215853-A | Preparation method of compound serving as farnesoid X receptor agonist | 四川科伦博泰生物医药股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-115197177-A | Environment-friendly tetrahydrofuran extractive distillation separation process | 扬州贝尔新环境科技有限公司 | 2022-10-18 | — | — | CN | disclosed |
| EP-4066896-A1 | G9A INHIBITOR | RIKEN (JP) | 2022-10-05 | — | — | EP | disclosed |
| CN-114685437-A | Eutectic crystal of axitinib and saccharin | 鲁南制药集团股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-112649524-B | Method for separating and detecting folic acid and folic acid optical isomer in folic acid | 重庆华邦胜凯制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-111517920-B | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-111517920-B | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-111517920-B | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-114316105-A | Method for removing involucra in PVC (polyvinyl chloride) by suspension method | 宜宾海丰和锐有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11241423-B2 | Antiproliferative compounds and methods of use thereof | CELGENE CORPORATION (US) | 2022-02-08 | — | — | US | disclosed |
| CN-114002352-A | Separation and detection method of folic acid and optical isomer thereof | 四川汇宇制药股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113461644-A | Method for recovering tetrahydrofuran from waste solvent | 江苏盈天化学有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-113402414-A | Benzoic acid derivative and preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2021-09-17 | — | — | CN | disclosed |
| WO-2021106988-A1 | G9a INHIBITOR | 杏林製薬株式会社 | 2021-06-03 | — | — | WO | disclosed |
| CN-111517920-A | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-111517920-A | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-111517920-A | Process for separating tetrahydrofuran-methanol-water by three-tower batch rectification | 青岛科技大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-111410674-A | Preparation method of low-cost high-yield high-purity 7-ketolithocholic acid | 上海慈瑞医药科技股份有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-108912090-B | Test strip for rapidly detecting total amount of alternariol and alternariol monomethyl ether | 北京农业质量标准与检测技术研究中心 | 2020-07-10 | — | — | CN | disclosed |
| CN-111233960-A | Preparation method of 3-hydroxy-6-ketocholanic acid with low cost and high yield | 上海慈瑞医药科技股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-20200163948-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2020-05-28 | — | — | US | disclosed |
| CN-111170991-A | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-111116685-A | Glucoside compound and preparation method and application thereof | 郑州市御合源生物科技有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111087320-A | Preparation method of propisochlor metabolite M5 | 天津阿尔塔科技有限公司 | 2020-05-01 | — | — | CN | disclosed |
| CN-106660991-B | Antiproliferative compounds and methods of use thereof | 细胞基因公司 | 2020-03-13 | — | — | CN | disclosed |
| US-10556877-B2 | Process for preparation of dapagliflozin | GLENMARK LIFE SCIENCES LIMITED (IN) | 2020-02-11 | — | — | US | disclosed |
| CN-110746376-A | Benzoisoselenazolone amine compound and preparation method and application thereof | 上海星叶医药科技有限公司 | 2020-02-04 | — | — | CN | disclosed |
| WO-2020020101-A1 | BENZISOSELENAZOLIDONE AMINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海星叶医药科技有限公司 | 2020-01-30 | — | — | WO | disclosed |
| EP-3166937-B1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2019-09-04 | — | — | EP | disclosed |
| CN-109232482-A | A kind of economic benefits and social benefits are thermally integrated abstraction distillation separation of tetrahydrofuran-methanol-water azeotropic mixture method | 重庆大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232482-A | A kind of economic benefits and social benefits are thermally integrated abstraction distillation separation of tetrahydrofuran-methanol-water azeotropic mixture method | 重庆大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232482-A | A kind of economic benefits and social benefits are thermally integrated abstraction distillation separation of tetrahydrofuran-methanol-water azeotropic mixture method | 重庆大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-108912090-A | A kind of test strips of quick detection alternariol and alternariol monomethyl ether total amount | 北京农业质量标准与检测技术研究中心 | 2018-11-30 | — | — | CN | disclosed |
| US-20180319798-A1 | 1,3,4,8-Tetrahydro-2H-Pyrido[1,2-a]Pyrazine Derivative and Use of the Same as HIV Integrase Inhibitor | JAPAN TOBACCO INC. (JP) | 2018-11-08 | — | — | US | disclosed |
| US-10065950-B2 | Substituted thiazoles as HIV integrase inhibitors | JAPAN TOBACCO INC. (JP) | 2018-09-04 | — | — | US | disclosed |
| US-20180221361-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2018-08-09 | — | — | US | disclosed |
| CN-105968073-B | The method of tetrahydrofuran in single column extracting rectifying recycling tetrahydrofuran-methanol-water | 青岛科技大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-105968073-B | The method of tetrahydrofuran in single column extracting rectifying recycling tetrahydrofuran-methanol-water | 青岛科技大学 | 2018-05-29 | — | — | CN | disclosed |
| US-9968596-B2 | Antiproliferative compounds and methods of use thereof | CELGENE CORPORATION (US) | 2018-05-15 | — | — | US | disclosed |
| US-20180127391-A1 | PROCESS FOR PREPARATION OF DAPAGLIFLOZIN | ALIVUS LIFE SCIENCES LIMITED (IN) | 2018-05-10 | — | — | US | disclosed |
| US-20180021325-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2018-01-25 | — | — | US | disclosed |
| US-9822092-B2 | ArylSulfonamide-based matrix metalloprotease inhibitors | NOVARTIS AG (CH) | 2017-11-21 | — | — | US | disclosed |
| US-9808451-B2 | Antiproliferative compounds and methods of use thereof | CELGENE CORPORATION (US) | 2017-11-07 | — | — | US | disclosed |
| CN-206188692-U | A device for extracting rectification recovery tetrahydrofuran | 天津天大凯泰化工科技有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106660991-A | Antiproliferative compounds and methods of use thereof | 细胞基因公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-2380881-B1 | NOVEL BICYCLIC HETEROCYCLIC COMPOUND | SUMITOMO DAINIPPON PHARMA CO LTD (JP) | 2017-01-25 | — | — | EP | disclosed |
| CN-205893131-U | Is tetrahydrofuran retrieved in extraction rectification methyl alcohol single tower system of aquatic tetrahydrofuran | 青岛科技大学 | 2017-01-18 | — | — | CN | disclosed |
| US-20170007590-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORP (US) | 2017-01-12 | — | — | US | disclosed |
| EP-2757093-B1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-9499514-B2 | Antiproliferative compounds and methods of use thereof | CELGENE CORPORATION (US) | 2016-11-22 | — | — | US | disclosed |
| WO-2016178148-A1 | PROCESS FOR PREPARATION OF DAPAGLIFLOZIN | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-11-10 | — | — | WO | disclosed |
| CN-106045894-A | 3(4)-Substituted alkoxyphenoxy hydrocarbon PPAR (peroxisome proliferator-activated receptor) agonist and application thereof | 天津医科大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105968073-A | Method for recycling tetrahydrofuran in tetrahydrofuran-methanol-water by single-tower extractive distillation | 青岛科技大学 | 2016-09-28 | — | — | CN | disclosed |
| CN-105968073-A | Method for recycling tetrahydrofuran in tetrahydrofuran-methanol-water by single-tower extractive distillation | 青岛科技大学 | 2016-09-28 | — | — | CN | disclosed |
| CN-105968073-A | Method for recycling tetrahydrofuran in tetrahydrofuran-methanol-water by single-tower extractive distillation | 青岛科技大学 | 2016-09-28 | — | — | CN | disclosed |
| CN-105891344-A | Technology for rapidly detecting and confirming multiple ultraviolet absorbers in cosmetics | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 2016-08-24 | — | — | CN | disclosed |
| CN-105891398-A | Technology for detecting multiple benzophenone ultraviolet absorbers in cosmetics and application thereof | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 2016-08-24 | — | — | CN | disclosed |
| CN-105891398-A | Technology for detecting multiple benzophenone ultraviolet absorbers in cosmetics and application thereof | 上海出入境检验检疫局动植物与食品检验检疫技术中心 | 2016-08-24 | — | — | CN | disclosed |
| CN-103012332-B | Use the method for packing tower distillation separation of tetrahydrofuran-methanol-water solvent slop | JIANGSU ALPHA PHARMACEUTICAL CO., LTD. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103012332-B | Use the method for packing tower distillation separation of tetrahydrofuran-methanol-water solvent slop | JIANGSU ALPHA PHARMACEUTICAL CO., LTD. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103012332-B | Use the method for packing tower distillation separation of tetrahydrofuran-methanol-water solvent slop | JIANGSU ALPHA PHARMACEUTICAL CO., LTD. (CN) | 2016-03-02 | — | — | CN | disclosed |
| US-20160009683-A1 | ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF | CELGENE CORPORATION | 2016-01-14 | — | — | US | disclosed |
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-9180123-B2 | N-link hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2134685-B1 | 7-NONSUBSTITUTED INDOLE DERIVATIVES AS MCL-1 INHIBITORS | ABBVIE INC (US) | 2015-09-02 | — | — | EP | disclosed |
| US-20150182513-A1 | N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150148326-A1 | Monobactams | PFIZER (US) | 2015-05-28 | — | — | US | disclosed |
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |
| US-9018384-B2 | N-link hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2015-04-28 | — | — | US | disclosed |
| EP-2540720-B1 | 1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE DERIVATIVE AND USE OF SAME AS HIV INTEGRASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2015-04-15 | — | — | EP | disclosed |
| US-8975439-B2 | Arylsulfonamide based matrix metalloprotease inhibitors | NOVARTIS AG (CH) | 2015-03-10 | — | — | US | disclosed |
| US-20150045398-A1 | ArylSulfonamide-Based Matrix Metalloprotease Inhibitors | NOVARTIS AG (CH) | 2015-02-12 | — | — | US | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
| US-20140364398-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140343031-A1 | N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. (US) | 2014-11-20 | — | — | US | disclosed |
| EP-2512474-B1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER (US) | 2014-11-05 | — | — | EP | disclosed |
| US-8853209-B2 | 1-oxyalkyl-2-carboxy-7-nonsubstituted indole derivatives | ABBVIE INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853258-B2 | C-linked hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8846933-B2 | N-link hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2757093-A1 | GUANIDINOBENZOIC ACID COMPOUND | Astellas Pharma Inc. (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-20140128363-A1 | N-Link Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER (US) | 2014-05-08 | — | — | US | disclosed |
| US-8697737-B2 | Raf modulators and methods of use | EXELIXIS, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| US-8664401-B2 | N-linked hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-03-04 | — | — | US | disclosed |
| CN-101647829-B | Quality control method of ginkgolide injection | JIANGSU KANION PHARMACEUTICAL | 2014-01-15 | — | — | CN | disclosed |
| US-20130303535-A1 | NOVEL BICYCLIC HETEROCYCLIC COMPOUND | Sumitomo Pharma Co., Ltd. (JP) | 2013-11-14 | — | — | US | disclosed |
| EP-2646436-A1 | MONOBACTAMS | Pfizer Inc (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20130252935-A1 | Monobactams | PFIZER INC. (US) | 2013-09-26 | — | — | US | disclosed |
| EP-1881825-B1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-07-24 | — | — | EP | disclosed |
| US-20130178468-A1 | HIV INTEGRASE INHIBITORS | VACCA JOSEPH P (US) | 2013-07-11 | — | — | US | disclosed |
| US-8471038-B2 | Bicyclic heterocyclic compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20130096105-A1 | ArylSulfonamide Based Matrix Metalloprotease Inhibitors | NOVARTIS AG (CH) | 2013-04-18 | — | — | US | disclosed |
| EP-2374788-B1 | INDANYL COMPOUNDS | DAIICHI SANKYO CO LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| CN-103012332-A | Method for separating waste solvent of tetrahydrofuran-methanol-water through rectification with packed tower | ALPHA PHARMACEUTICAL CO LTD JIANGSU PROVINCE | 2013-04-03 | — | — | CN | disclosed |
| CN-103012332-A | Method for separating waste solvent of tetrahydrofuran-methanol-water through rectification with packed tower | ALPHA PHARMACEUTICAL CO LTD JIANGSU PROVINCE | 2013-04-03 | — | — | CN | disclosed |
| CN-103012332-A | Method for separating waste solvent of tetrahydrofuran-methanol-water through rectification with packed tower | ALPHA PHARMACEUTICAL CO LTD JIANGSU PROVINCE | 2013-04-03 | — | — | CN | disclosed |
| US-8362063-B2 | Arylsulfonamide based matrix metalloprotease inhibitors | NOVARTIS AG (CH) | 2013-01-29 | — | — | US | disclosed |
| EP-2540720-A1 | 1,3,4,8-TETRAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE DERIVATIVE AND USE OF SAME AS HIV INTEGRASE INHIBITOR | Japan Tobacco, Inc. (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-20120302542-A1 | MONOBACTAMS | PFIZER INC | 2012-11-29 | — | — | US | disclosed |
| EP-2512474-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-10-24 | — | — | EP | disclosed |
| US-8293731-B2 | HIV integrase inhibitors | Merck Sharp + Dohme Corp. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120258954-A1 | ArylSulfonamide Based Matrix Metalloprotease Inhibitors | NOVARTIS AG (CH) | 2012-10-11 | — | — | US | disclosed |
| US-20120258948-A1 | N-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | PFIZER INC. | 2012-10-11 | — | — | US | disclosed |
| US-8252781-B2 | 1,2-diazetidin-3-one derivatives and drugs containing same | KOWA COMPANY, LTD. (JP) | 2012-08-28 | — | — | US | disclosed |
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202777-A1 | C-Linked Hydroxamic Acid Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2012-08-09 | — | — | US | disclosed |
| US-8222424-B2 | Arylsulfonamide-based matrix metalloprotease inhibitors | NOVARTIS AG (CH) | 2012-07-17 | — | — | US | disclosed |
| WO-2012073138-A1 | MONOBACTAMS | PFIZER INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| CN-101647830-B | Quality control method of ginkgolide medicinal preparation | JIANGSU KANION PHARMACEUTICAL | 2012-05-23 | — | — | CN | disclosed |
| US-8183272-B2 | Indanyl compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-22 | — | — | US | disclosed |
| US-8173631-B2 | Cyclic amine compounds | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20120108564-A1 | 1,3,4,8-Tetrahydro-2H-Pyrido[1,2-a]Pyradine Derivatives and Use Thereof as HIV Integrase Inhibitor | JAPAN TOBACCO INC. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20110319468-A1 | CYCLIC AMINE COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20110319359-A1 | INDANYL COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20110294804-A1 | NOVEL BICYCLIC HETEROCYCLIC COMPOUND | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-12-01 | — | — | US | disclosed |
| US-20110275703-A1 | SUBSTITUTED SPIROKETAL DERIVATIVES AND USE THEREOF AS THERAPEUTIC DRUG FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110275621-A1 | HIV INTEGRASE INHIBITORS | SCHERING CORPORATION | 2011-11-10 | — | — | US | disclosed |
| US-20110263599-A1 | 7-NONSUBSTITUTED INDOLE MCL-1 INHIBITORS | ABBOTT LABORATORIES | 2011-10-27 | — | — | US | disclosed |
| EP-2380881-A1 | NOVEL BICYCLIC HETEROCYCLIC COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-10-26 | — | — | EP | disclosed |
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2358736-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | Intermune, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| EP-2348019-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVE AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-7981888-B2 | 1-oxyalkyl-2-carboxyl-7-nonsubstituted indole derivatives | ABBOTT LABORATORIES (US) | 2011-07-19 | — | — | US | disclosed |
| US-7968564-B2 | HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-06-28 | — | — | US | disclosed |
| WO-2011073845-A1 | N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| US-20110071145-A1 | Raf Modulators And Methods Of Use | EXELIXIS, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20110014186-A1 | ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS | NOVARTIS AG (CH) | 2011-01-20 | — | — | US | disclosed |
| EP-2268612-A1 | ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS | Novartis AG (CH) | 2011-01-05 | — | — | EP | disclosed |
| US-7846959-B2 | Raf modulators and methods of use | EXELIXIS, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20100204201-A1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2010-08-12 | — | — | US | disclosed |
| US-7741315-B2 | HIV integrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20100144694-A1 | 1,2-DIAZETIDIN-3-ONE DERIVATIVES AND DRUGS CONTAINING SAME | KOWA COMPANY, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| EP-1682553-B1 | THIENOPYRAZOLES | AVENTIS PHARMA INC (US) | 2010-05-19 | — | — | EP | disclosed |
| US-20100119479-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| US-20100093744-A1 | THIOGLUCOSE SPIROKETAL DERIVATIVE AND USE THEREOF AS THERAPEUTIC AGENT FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-04-15 | — | — | US | disclosed |
| CN-101647830-A | Quality control method of ginkgolide medicinal preparation | JIANGSU KANION PHARMACEUTICAL | 2010-02-17 | — | — | CN | disclosed |
| CN-101647829-A | A quality control method of ginkgolide injection | JIANGSU KANION PHARMACEUTICAL | 2010-02-17 | — | — | CN | disclosed |
| WO-2009118292-A1 | ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS | NOVARTIS AG (CH) | 2009-10-01 | — | — | WO | disclosed |
| US-20090181942-A1 | TRICYCLIC COMPOUNDS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-2072522-A1 | THIOGLUCOSE SPIROKETAL DERIVATIVE AND USE THEREOF AS THERAPEUTIC AGENT FOR DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-20090131397-A1 | ESTROGEN MODULATORS | PFIZER INC. | 2009-05-21 | — | — | US | disclosed |
| US-20090124616-A1 | 7-NONSUBSTITUTED INDOLE MCL-1 INHIBITORS | ABBOTT LABORATORIES (US) | 2009-05-14 | — | — | US | disclosed |
| EP-2048153-A1 | SUBSTITUTED SPIROKETAL DERIVATIVE AND USE THEREOF AS DRUG FOR TREATING DIABETES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-20090054399-A1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2009-02-26 | — | — | US | disclosed |
| US-7470715-B2 | Estrogen modulators | PFIZER INC. (US) | 2008-12-30 | — | — | US | disclosed |
| EP-1966170-A2 | ESTROGEN MODULATORS | Pfizer Products Inc. (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1939205-A1 | TRICYCLIC COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2008-07-02 | — | — | EP | disclosed |
| EP-1881825-A2 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2008-01-30 | — | — | EP | disclosed |
| US-20080009488-A1 | Raf Modulators and Methods of Use | EXELIXIS, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| US-7285572-B2 | CaSR antagonist | JAPAN TOBACCO INC. (JP) | 2007-10-23 | — | — | US | disclosed |
| WO-2007072164-A2 | ESTROGEN MODULATORS | PFIZER PRODUCTS INC. (US) | 2007-06-28 | — | — | WO | disclosed |
| US-20070149564-A1 | ESTROGEN MODULATORS | PFIZER INC. (US) | 2007-06-28 | — | — | US | disclosed |
| US-7208505-B2 | β3 adrenergic agonists | ELI LILLY AND COMPANY (US) | 2007-04-24 | — | — | US | disclosed |
| US-7179479-B1 | Mosquito repellent isolated from Foeniculum vulgare fruit | NATUROBIOTECH CO., LTD. (KR) | 2007-02-20 | — | — | US | disclosed |
| EP-1751124-A2 | RAF MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2006121831-A2 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| EP-1421078-B1 | INDOLE DERIVATIVES AS BETA-3 ADRENERGIC AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES | LILLY CO ELI (US) | 2006-09-27 | — | — | EP | disclosed |
| US-7098212-B2 | Piperazine derivatives | BLUMBERG LAURA C | 2006-08-29 | — | — | US | disclosed |
| US-7087635-B2 | 3-substituted oxindole β3 agonists | ELI LILLY AND COMPANY (US) | 2006-08-08 | — | — | US | disclosed |
| US-20060135572-A1 | CaSR antagonist | JAPAN TOBACCO INC. (JP) | 2006-06-22 | — | — | US | disclosed |
| CN-1257707-C | An insect repellent isolated from foeniculum vulgare fruit | NATUROBIOTECH CO LTD (KR) | 2006-05-31 | — | — | CN | disclosed |
| EP-1444224-B1 | 3-SUBSTITUTED OXINDOLE BETA-3 AGONISTS | LILLY CO ELI (US) | 2006-05-03 | — | — | EP | disclosed |
| US-7030242-B2 | Selective inhibition of aggrecanase in osteoarthritis treatment | PFIZER INC (US) | 2006-04-18 | — | — | US | disclosed |
| EP-1630157-A1 | CaSR ANTAGONIST | JAPAN TOBACCO INC. (JP) | 2006-03-01 | — | — | EP | disclosed |
| WO-2005112932-A2 | RAF MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050227997-A1 | 1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-4-aminoacetyl-3-methyl-piperazine-2-carboxylic acid hydroxyamide; potent enzyme inhibitor of metalloproteinases, for treating joint disease, prevent cartilage destruction | NOE MARK C | 2005-10-13 | — | — | US | disclosed |
| EP-1583533-A1 | USE OF PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS | Pfizer Products Inc. (US) | 2005-10-12 | — | — | EP | disclosed |
| US-20050215549-A1 | TACE inhibitors | MCCLURE KIM F | 2005-09-29 | — | — | US | disclosed |
| US-20050159473-A1 | 3-Substituted oxindole beta3 agonists | SALL DANIEL J (US) | 2005-07-21 | — | — | US | disclosed |
| US-6911463-B2 | 3-substituted oxindole β-3 agonists | ELI LILLY AND COMPANY (US) | 2005-06-28 | — | — | US | disclosed |
| EP-1104412-B1 | TACE INHIBITORS | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050080110-A1 | Beta 3 adrenergic agonists | SALL DANIEL JON (US) | 2005-04-14 | — | — | US | disclosed |
| US-20040242668-A1 | 3-substituted oxindole beta-3 agonists | SALL DANIEL JON (US) | 2004-12-02 | — | — | US | disclosed |
| EP-1444224-A2 | 3-SUBSTITUTED OXINDOLE BETA-3 AGONISTS | ELI LILLY AND COMPANY (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1438298-A1 | PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY | Pfizer Products Inc. (US) | 2004-07-21 | — | — | EP | disclosed |
| EP-1421078-A1 | BETA-3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040092529-A1 | Methods of using piperazine derivatives | PFIZER INC | 2004-05-13 | — | — | US | disclosed |
| WO-2004039376-A1 | USE OF PIPERAZINE DERIVATIVES AS CCR1 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2004-05-13 | — | — | WO | disclosed |
| US-6713489-B2 | TREATMENT OF ATHEROSCLEROSIS, OBESITY, DIABETES, HYPERLIPIDEMIA, HYPERLIPOPROTEINEMIA, HYPERCHOLESTEROLEMIA, HYPERTRIGLYCERIDEMIA, HYPOALPHALIPOPROTEINEMIA, PANCREATITIS, MYOCARDIAL INFARCTION, STROKE, RESTENOSIS, OR SYNDROME X | PFIZER INC | 2004-03-30 | — | — | US | disclosed |
| US-20040034034-A1 | Novel piperazine derivatives | BLUMBERG LAURA C (US) | 2004-02-19 | — | — | US | disclosed |
| US-6646123-B2 | Antitumor | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| CN-1454077-A | Insect repellent isolated from the fruit of the plant Foeniculum vulgare | NATUROBIOTECH CO LTD (KR) | 2003-11-05 | — | — | CN | disclosed |
| US-20030181441-A1 | TACE INHIBITORS | McCLURE Kim (US) | 2003-09-25 | — | — | US | disclosed |
| US-20030162971-A1 | Pentacyclic compound | DAIICHI PHARMACEUTICAL CO., LTD. | 2003-08-28 | — | — | US | disclosed |
| EP-1041072-B1 | Dioxocyclopentyl hydroxamic acids | PFIZER PROD INC (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2003035627-A1 | PIPERAZINE DERIVATIVES WITH CCR1 RECEPTOR ANTAGONIST ACTIVITY | PFIZER PRODUCTS INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| US-6545151-B2 | Taxol derivative; antitumor agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-08 | — | — | US | disclosed |
| EP-1296637-A1 | AN INSECT REPELLENT ISOLATED FROM I FOENICULUM VULGARE /I FRUIT | Naturobiotech Co., Ltd. (KR) | 2003-04-02 | — | — | EP | disclosed |
| WO-2003016307-A1 | β3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003016276-A2 | 3-SUBSTITUTED OXINDOLE BETA-3 AGONISTS | ELI LILLY AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| US-20020132806-A1 | 7-[(4'-trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and methods of inhibiting the secretion of apolipoprotein B | RUGGERI ROGER (US) | 2002-09-19 | — | — | US | disclosed |
| US-6369075-B1 | 7[4′-trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and method of inhibiting the secretion of apolipoprotein B | PFIZER, INC. | 2002-04-09 | — | — | US | disclosed |
| WO-2002002065-A1 | AN INSECT REPELLENT ISOLATED FROM FOENICULUM VULGARE FRUIT | NATUROBIOTECH CO., LTD. (KR) | 2002-01-10 | — | — | WO | disclosed |
| US-20010041796-A1 | Pentacyclic compound | TERASAWA HIROFUMI (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0826688-B1 | PENTACYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-1104412-A1 | TACE INHIBITORS | Pfizer Products Inc. (US) | 2001-06-06 | — | — | EP | disclosed |
| EP-1099701-A1 | 7-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and methods of inhibiting the secretion of apolipoprotein B | Pfizer Products Inc. (US) | 2001-05-16 | — | — | EP | disclosed |
| US-6214870-B1 | ANTIARTHRITIC AGENTS; ANTICANCER AGENTS | PFIZER INC | 2001-04-10 | — | — | US | disclosed |
| US-6211363-B1 | TAXANE COMPOUNDS; ANTITUMOR AGENTS | DAIICHI PHARAMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-1081137-A1 | Selective inhibitors of aggrecanase in osteoarthritis treatment | Pfizer Products Inc. (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6150391-A | Diazabicyclo-octane derivatives as 5-HT receptor ligands | MERCK SHARP & DOHME LTD. | 2000-11-21 | — | — | US | disclosed |
| EP-1041072-A1 | Dioxocyclopentyl hydroxamic acids | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |
| US-6075140-A | A TAXOL DERIVATIVE CONTAINING PENTACYCLIC RING IN WHICH 9 AND 10 POSITION HYDROXYL GROUP ARE CHANGED TO CYCLIC ACETAL GROUP IS USEFUL AS ANTITUMOR AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-06-13 | — | — | US | disclosed |
| WO-2000009492-A1 | TACE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| US-5998398-A | HERPES VIRUS | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0886635-A1 | 2-AMINO-5,6-DICHLOROBENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 1998-12-30 | — | — | EP | disclosed |
| EP-0826688-A1 | PENTACYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0433897-B1 | Process for preparing an optically active cyclobutane nucleoside | SQUIBB & SONS INC (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1997028162-A1 | DIAZABICYCLO-OCTANE DERIVATIVES AS 5-HT RECEPTOR LIGANDS | MERCK SHARP & DOHME LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997025316-A1 | 2-AMINO-5,6-DICHLOROBENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 1997-07-17 | — | — | WO | disclosed |
| EP-0396427-B1 | Pesticidal 1-arylimidazoles | RHONE POULENC AGROCHIMIE (FR) | 1995-09-13 | — | — | EP | disclosed |
| US-5399577-A | Lipoxygenase and cyclooxygenase inhibitor, antiasthma, antiinflammatory | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0633254-A1 | NOVEL ISOXAZOLE DERIVATIVE AND SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| US-5306837-A | Intermediates for an optically active cyclobutane nucleoside | E. R. SQUIBB & SONS, INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-5256806-A | Intermediates for the preparation of optically active cyclobutane nucleoside | E. R. SQUIBB & SONS, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5223525-A | Pesticidal 1-arylimidazoles | RHONE-POULENC AG COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| US-5198583-A | Optically active cyclobutane nucleoside and intermediates, therefor | E. R. SQUIBB & SONS, INC. (US) | 1993-03-30 | — | — | US | disclosed |
| US-H1142-H | Antiviral agent against herpes and varicella-zoster viruses | E. R. SQUIBB & SONS, INC. | 1993-02-02 | — | — | US | disclosed |
| EP-0484165-A1 | Pesticidal 1-arylimidazoles | RHONE-POULENC AGROCHIMIE (FR) | 1992-05-06 | — | — | EP | disclosed |
| US-5064961-A | PROCESS FOR PREPARING AN OPTICALLY ACTIVE CYCLOBUTANE NUCLEOSIDE | E. R. SQUIBB & SONS, INC. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0129136-B1 | ANTIHYPERTENSIVE COMPOSITION | MERCK & CO. INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0433897-A2 | Process for preparing an optically active cyclobutane nucleoside | E.R. SQUIBB & SONS, INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0396427-A1 | Pesticidal 1-arylimidazoles | RHONE-POULENC AGROCHIMIE (FR) | 1990-11-07 | — | — | EP | disclosed |
| EP-0248916-A1 | Method for separation of 3S,7R-3,4,5,6,7,8,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one from its 3S,7S-diastereomer | C.R.C. Compagnia di Ricerca Chimica S.p.A. (IT) | 1987-12-16 | — | — | EP | disclosed |
| EP-0248916-A1 | Method for separation of 3S,7R-3,4,5,6,7,8,9,10,11,12-decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one from its 3S,7S-diastereomer | C.R.C. Compagnia di Ricerca Chimica S.p.A. (IT) | 1987-12-16 | — | — | EP | disclosed |