Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5664722 | 0.79 | ALDH1A1 (0.40) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL4198308 | 0.76 | TDP1 (0.44) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL1516264 | 0.76 | NPC1 (0.45) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1515297 | 0.76 | L3MBTL1 (0.54) | KDM4ELMNAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL176731 | 0.75 | MEN1 (0.56) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL29686686 | 0.72 | RAB9A (0.54) | LMNAALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL16532701 | 0.71 | TUBB4A (0.49) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5664580 | 0.71 | HDAC3 (0.45) | KDM4ELMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5666957 | 0.70 | HDAC3 (0.43) | KDM4EL3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL22346302 | 0.70 | FDPS (0.51) | LMNAALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716137-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | Pfizer Products Incorporated (US) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005080373-A1 | SUBSTITUTED QUINOLINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | disclosed |