Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663265 | 0.94 | FDPS (0.39) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL5665099 | 0.90 | FDPS (0.45) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL5662741 | 0.87 | FDPS (0.42) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL5667969 | 0.86 | FDPS (0.52) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL5662316 | 0.86 | FDPS (0.43) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL5662383 | 0.84 | FDPS (0.41) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL6306477 | 0.82 | LMNA (0.43) | L3MBTL1CYP1A2CYP2C19NPSR1CYP2C9 | |
| SCHEMBL5663721 | 0.81 | FDPS (0.39) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL6320488 | 0.78 | L3MBTL1 (0.42) | FDPSL3MBTL1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL6314585 | 0.77 | LMNA (0.41) | L3MBTL1CYP1A2CYP2C19NPSR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482954-A4 | ALPHA-SUBSTITUTED ARYLALKYL PHOSPHONATE DERIVATIVES | ILEX PRODUCTS INC (US) | 2006-05-03 | — | — | EP | claimed |
| US-20050124586-A1 | Alpha-substituted arylalkyl phosphonate derivatives | ILEX PRODUCTS, INC. | 2005-06-09 | — | — | US | claimed |
| EP-1482954-A2 | ALPHA-SUBSTITUTED ARYLALKYL PHOSPHONATE DERIVATIVES | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003069302-A2 | ALPHA-SUBSTITUTED ARYLALKYL PHOSPHONATE DERIVATIVES | ILEX PRODUCTS, INC. (US) | 2003-08-21 | — | — | WO | claimed |
| US-20050124586-A1 | Alpha-substituted arylalkyl phosphonate derivatives | ILEX PRODUCTS, INC. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124586-A1 | Alpha-substituted arylalkyl phosphonate derivatives | APOB, APOL1, LDLR | FDPS 899/4885L3MBTL1 1215/4885CYP1A2 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.