Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323025 | 0.87 | L3MBTL1 (0.39) | L3MBTL1KMT2AHMGCRMAPTFDPS | |
| SCHEMBL5664672 | 0.78 | FDPS (0.42) | L3MBTL1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5663265 | 0.75 | FDPS (0.39) | L3MBTL1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5662499 | 0.74 | HMGCR (0.63) | L3MBTL1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5662316 | 0.72 | FDPS (0.43) | L3MBTL1CYP1A2CYP2C19NPSR1HMGCR | |
| SCHEMBL6060960 | 0.72 | PDE4D (0.43) | L3MBTL1NPSR1HMGCRALOX15GAA | |
| SCHEMBL6061529 | 0.69 | PDE4D (0.40) | L3MBTL1KMT2ANPSR1HMGCRALOX15 | |
| SCHEMBL5665099 | 0.68 | FDPS (0.45) | L3MBTL1CYP1A2CYP2C19NPSR1ALOX15 | |
| SCHEMBL6306477 | 0.67 | LMNA (0.43) | L3MBTL1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6305878 | 0.67 | KCNQ3 (0.35) | L3MBTL1KMT2ANPSR1HMGCRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124581-A1 | Alpha-substituted heteroarylalkyl phosphonate derivatives | PHAN HIEU T (CH) | 2005-06-09 | — | — | US | claimed |
| US-20050124581-A1 | Alpha-substituted heteroarylalkyl phosphonate derivatives | PHAN HIEU T (CH) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124581-A1 | Alpha-substituted heteroarylalkyl phosphonate derivatives | APOB, APOL1, LDLR | L3MBTL1 1161/4885KMT2A 3039/4885CYP1A2 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.