Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501059 | 0.86 | CTRB1 (0.42) | MAOBGRM2 | |
| SCHEMBL567091 | 0.77 | LMNA (0.49) | LMNAMAOBMAOABCHECYP2C19 | |
| SCHEMBL567665 | 0.77 | LMNA (0.49) | LMNAMAOBMAOABCHECYP2C19 | |
| SCHEMBL7987732 | 0.74 | MEN1 (0.49) | LMNAMAOBMAOAMEN1KMT2A | |
| SCHEMBL536617 | 0.73 | GLA (0.47) | MEN1KMT2AALDH1A1NPSR1SLC6A2 | |
| SCHEMBL567327 | 0.73 | GLA (0.47) | MEN1KMT2AALDH1A1NPSR1SLC6A2 | |
| SCHEMBL5380212 | 0.72 | MEN1 (0.50) | LMNAMAOBMEN1KMT2AKDM4C | |
| SCHEMBL3994040 | 0.72 | MEN1 (0.50) | LMNAMAOBMEN1KMT2AKDM4C | |
| SCHEMBL567024 | 0.71 | ALDH1A1 (0.43) | LMNAKMT2AALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL7629569 | 0.70 | CTRB1 (0.53) | MAOBGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010157-A1 | DIOXANE DERIVATIVES AND A PROCESS FOR THEIR PREPARATION | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2003-02-06 | — | — | WO | disclosed |