Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367720 | 0.84 | CA1 (0.41) | KCNA5ALDH1A1LMNACA1CA2 | |
| SCHEMBL10700915 | 0.83 | KCNA5 (0.50) | KCNA5ALDH1A1LMNACA1CA2 | |
| SCHEMBL5824341 | 0.80 | OPRM1 (0.47) | KCNA5ALDH1A1LMNAHPGDTRPM8 | |
| SCHEMBL8498802 | 0.78 | KCNA5 (0.46) | KCNA5ALDH1A1LMNACA1CA2 | |
| SCHEMBL8336802 | 0.77 | KCNA5 (0.44) | KCNA5ALDH1A1LMNACA1CA2 | |
| SCHEMBL27812850 | 0.75 | ALDH1A1 (0.49) | KCNA5ALDH1A1LMNAHPGDTRPM8 | |
| SCHEMBL1872252 | 0.75 | ALDH1A1 (0.49) | KCNA5ALDH1A1LMNACA1CA2 | |
| SCHEMBL2392586 | 0.75 | OPRM1 (0.45) | KCNA5ALDH1A1LMNAHPGDTRPM8 | |
| SCHEMBL7540738 | 0.74 | KDM1A (0.49) | KCNA5ALDH1A1LMNAHPGDTRPM8 | |
| SCHEMBL17847282 | 0.74 | HTR2C (0.46) | KCNA5ALDH1A1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723102-A2 | N-SUBSTITUTED BENZENE SULFONAMIDES | Elan Pharmaceuticals, Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005090296-A2 | N-SUBSTITUTED BENZENE SULFONAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |