Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.34 |
| ▸ | PTGFR | P43088 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434526 | 0.82 | SLC9A1 (0.42) | HTR2BNFKB1PTGER3PTGER2PTGER4 | |
| SCHEMBL28993114 | 0.79 | PTGER3 (0.56) | NFKB1PTGER3PTGER2PTGER4TBXA2R | |
| SCHEMBL5436433 | 0.78 | NFKB1 (0.64) | HTR2BNFKB1BACE1MAOBGRIN1 | |
| SCHEMBL5670302 | 0.77 | HTT (0.41) | NFKB1PTGER3PTGER2PTGER4BACE1 | |
| SCHEMBL5436272 | 0.76 | MAOB (0.50) | HTR2BMAOBGRIN1GRIN2BNFE2L2 | |
| SCHEMBL5423688 | 0.73 | HSD11B1 (0.61) | HTR2BNFKB1NFE2L2 | |
| SCHEMBL5426825 | 0.73 | HDAC1 (0.54) | NFKB1MAOBGRIN1GRIN2BGRIN2D | |
| SCHEMBL5430628 | 0.73 | ALDH1A1 (0.48) | HTR2BNFKB1NFE2L2 | |
| SCHEMBL5672084 | 0.73 | HTR2B (0.47) | HTR2BGRIN1GRIN2B | |
| SCHEMBL5432216 | 0.72 | NFKB1 (0.44) | HTR2BNFKB1BACE1MAOBGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |