Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 4/20 | 0.42 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493489 | 1.00 | ENPP3 (0.43) | ENPP3ENPP1FABP4FABP3FABP5 | |
| SCHEMBL6139065 | 0.88 | ENPP3 (0.43) | ENPP3ENPP1FABP4FABP3FABP5 | |
| SCHEMBL5670976 | 0.80 | KEAP1 (0.41) | EPHX2 | |
| SCHEMBL7494636 | 0.80 | KEAP1 (0.41) | EPHX2 | |
| SCHEMBL7495927 | 0.77 | TDP1 (0.40) | ENPP3ENPP1FABP4FABP5GAA | |
| SCHEMBL5672285 | 0.77 | TDP1 (0.40) | ENPP3ENPP1FABP4FABP5GAA | |
| SCHEMBL5670961 | 0.77 | FABP4 (0.41) | FABP4FABP5CXCL8PPARA | |
| SCHEMBL5672253 | 0.74 | KMT2A (0.41) | — | |
| SCHEMBL5673248 | 0.74 | KMT2A (0.41) | — | |
| SCHEMBL7490542 | 0.74 | TDP1 (0.43) | ENPP3ENPP1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030208077-A1 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI (FR) | 2003-11-06 | — | — | US | claimed |
| EP-1021449-B1 | HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI SYNTHELABO (FR) | 2002-01-02 | — | — | EP | claimed |
| EP-1021449-A1 | HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2000-07-26 | — | — | EP | claimed |
| WO-1999018110-A1 | HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 1999-04-15 | — | — | WO | claimed |
| US-7153969-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-AVENTIS (FR) | 2006-12-26 | — | — | US | disclosed |
| US-6894186-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-SYNTHELABO (FR) | 2005-05-17 | — | — | US | disclosed |
| US-20040260110-A1 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI (FR) | 2004-12-23 | — | — | US | disclosed |
| US-20030208077-A1 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI (FR) | 2003-11-06 | — | — | US | disclosed |
| US-6573381-B1 | Useful as intermediates, notably for the synthesis of methyl (S)-2(2-chlorophenyl)-2(4,5,6,7-tetrahydrothieno(3,2-c)-5-pyridyl)acetate or clopidrogel | SANOFI-SYNTHELABO (FR) | 2003-06-03 | — | — | US | disclosed |
| EP-1021449-B1 | HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI SYNTHELABO (FR) | 2002-01-02 | — | — | EP | disclosed |
| EP-1021449-A1 | HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999018110-A1 | HYDROXYACETIC ESTER DERIVATIVES, PREPARATION METHOD AND USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 1999-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208077-A1 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | HAAO, HTR3C, HTR3A | ENPP3 1075/4885ENPP1 2381/4885FABP4 2001/4885 |
| US-20040260110-A1 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | HAAO, HTR3C, HTR3A | ENPP3 1075/4885ENPP1 2381/4885FABP4 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.