Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 2/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493489 | 0.88 | ENPP3 (0.43) | ENPP3ENPP1FABP3FABP4FABP5 | |
| SCHEMBL5671763 | 0.88 | ENPP3 (0.43) | ENPP3ENPP1FABP3FABP4FABP5 | |
| SCHEMBL6139499 | 0.81 | EPHX2 (0.39) | GAAEPHX2ABCB11 | |
| SCHEMBL28560399 | 0.79 | ABCB11 (0.39) | ABCB11CXCL8 | |
| SCHEMBL26301826 | 0.79 | ABCB11 (0.39) | ABCB11CXCL8 | |
| SCHEMBL2169427 | 0.79 | ABCB11 (0.39) | ABCB11CXCL8 | |
| SCHEMBL6139230 | 0.77 | PSEN1 (0.43) | ABCB11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28824902 | 0.77 | PSEN1 (0.43) | ABCB11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6138912 | 0.76 | MAPK1 (0.39) | ABCB11 | |
| SCHEMBL28555501 | 0.76 | LMNA (0.42) | ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894186-B2 | Hydroxyacetic ester derivatives, preparation method and use as synthesis intermediates | SANOFI-SYNTHELABO (FR) | 2005-05-17 | — | — | US | claimed |