SCHEMBL56753

SCHEMBL56753

CC(C)C[C@H](CC(=O)O)NC(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.51
CTSK P43235 3/20 0.51
CTSL P07711 2/20 0.51
CTSB P07858 1/20 0.51
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
AAK1 Q2M2I8 4/20 0.47
CYP2D6 P10635 1/20 0.45
CAPN1 P07384 1/20 0.45
ATM Q13315 1/20 0.42
PLA2G10 O15496 1/20 0.42
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56754 1.00 CTSS (0.51) CTSSCTSKCTSLCTSBCA1
SCHEMBL4934738 1.00 CTSS (0.51) CTSSCTSKCTSLCTSBCA1
SCHEMBL6684772 0.88 CA1 (0.49) CTSSCTSKCTSLCTSBCA1
SCHEMBL19227630 0.88 CA1 (0.58) CTSSCTSKCTSLCTSBCA1
SCHEMBL24387611 0.85 CA1 (0.49) CTSSCTSKCTSLCTSBCA1
SCHEMBL24387604 0.85 CA1 (0.49) CTSSCTSKCTSLCTSBCA1
SCHEMBL9506672 0.84 CYP2D6 (0.48) CTSSCTSKCTSLCTSBCA1
SCHEMBL7434716 0.84 PLA2G10 (0.51) CTSSCTSKCTSLCTSBCA1
SCHEMBL24900084 0.84 CA1 (0.47) CTSSCTSKCTSLCTSBCA1
SCHEMBL2385476 0.83 CTSK (0.49) CTSSCTSKCTSLCTSBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PEPTIDREAM INC (JP) 2026-01-15 US disclosed
EP-4534524-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF PeptiDream Inc. (JP) 2025-04-09 EP disclosed
US-8129411-B2 Organic compounds NOVARTIS AG (CH) 2012-03-06 US disclosed
EP-2420491-A1 3 , 5-substitued piperidine compounds as renin inhibitors Novartis AG (CH) 2012-02-22 EP disclosed
US-20090192148-A1 Organic Compounds NOVARTIS AG (CH) 2009-07-30 US disclosed
EP-1968940-A1 3 , 5-SUBSTITUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS Novartis AG (CH) 2008-09-17 EP disclosed
WO-2007077005-A1 3 , 5-SUBSTITΓUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS NOVARTIS AG (CH) 2007-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015313-A1 AMINO ACID ACTIVE ESTER AND SALT THEREOF NSUN3, BCAT1, SLC43A1 CTSS 4022/4885CTSK 4661/4885CTSL 1563/4885
US-20090192148-A1 Organic Compounds REN, ACE, AGTR1 CTSS 301/4885CTSK 863/4885CTSL 432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.