Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677122 | 1.00 | ADORA2A (0.40) | ADORA2AADORA1CNR1SIGMAR1MAOB | |
| SCHEMBL15613459 | 0.83 | HTR1A (0.47) | MAOBMAOAMTNR1AMTNR1BTSHR | |
| SCHEMBL10613374 | 0.83 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL10927874 | 0.81 | TSHR (0.48) | MEN1CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL10927872 | 0.81 | TSHR (0.48) | MEN1CYP1A2CYP3A4TSHRCYP2C19 | |
| SCHEMBL5680214 | 0.80 | SIGMAR1 (0.44) | ADORA2AADORA1CNR1SIGMAR1PYGL | |
| SCHEMBL5675579 | 0.80 | SIGMAR1 (0.44) | ADORA2AADORA1CNR1SIGMAR1PYGL | |
| SCHEMBL5675691 | 0.80 | SIGMAR1 (0.44) | ADORA2AADORA1CNR1SIGMAR1PYGL | |
| SCHEMBL5675575 | 0.80 | SIGMAR1 (0.44) | ADORA2AADORA1CNR1SIGMAR1PYGL | |
| SCHEMBL12362855 | 0.80 | KDM1A (0.45) | ADORA2AADORA1MAOBMAOAPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414426-B1 | CARBOCYCLIC HYDRAZINO INHIBITORS OF COPPER-CONTAINING AMINE OXIDASES | BIOTIE THERAPIES CORP (FI) | 2006-03-01 | — | — | EP | disclosed |
| US-6982286-B2 | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases | BIOTIE THERAPIES CORP. (FI) | 2006-01-03 | — | — | US | disclosed |
| US-20040236108-A1 | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases | BIOTIE THERAPIES CORPORATION (FI) | 2004-11-25 | — | — | US | disclosed |
| US-20030125360-A1 | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases | BIOTIE THERAPIES CORP. | 2003-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236108-A1 | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases | AOC2, VCAM1, AOC3 | ADORA2A 3307/4885ADORA1 1769/4885CNR1 1276/4885 |
| US-20030125360-A1 | Carbocyclic hydrazino inhibitors of copper-containing amine oxidases | AOC2, AOC3, AOC1 | ADORA2A 3240/4885ADORA1 1740/4885CNR1 1207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.