Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304191 | 0.73 | HCAR3 (0.44) | HSD11B1ALDH1A1HTT | |
| SCHEMBL531260 | 0.64 | LMNA (0.31) | LMNA | |
| Toluene SCHEMBL11325304 | 0.63 | LMNA (0.69) | LMNATSHRALOX12ACHEHTT | |
| Toluene SCHEMBL28200424 | 0.63 | TSHR (0.52) | LMNATSHRALOX12ACHEHSD11B1 | |
| Toluene SCHEMBL6404501 | 0.63 | LMNA (0.52) | LMNATSHRALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL1573659 | 0.61 | LMNA (0.65) | LMNATSHRALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL27330916 | 0.61 | ACHE (0.65) | LMNATSHRALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL4458162 | 0.61 | LMNA (0.65) | LMNATSHRALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL10611921 | 0.61 | LMNA (0.65) | LMNATSHRALOX12ACHEALDH1A1 | |
| Toluene SCHEMBL10900065 | 0.61 | LMNA (0.65) | LMNATSHRALOX12ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035341-A1 | PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS | MINASOLVE (FR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010100390-A1 | CATALYTIC POLYMERIZATION METHOD FOR 1,4-DIOXANE-2,5-DIONES, AND CORRESPONDING POLYMERS | MINASOLVE (FR) | 2010-09-10 | — | — | WO | disclosed |