Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9473864 | 0.74 | LTB4R (0.48) | — | |
| SCHEMBL1874184 | 0.73 | CYP2C9 (0.42) | CA2CA1CA9CA6CA12 | |
| SCHEMBL5679972 | 0.71 | CISD1 (0.37) | CA2CA1CA9CA12CA5A | |
| SCHEMBL30988956 | 0.70 | CA2 (0.50) | CA2CA1CA9CA6CA12 | |
| SCHEMBL407413 | 0.70 | CA2 (0.50) | CA2CA1CA9CA6CA12 | |
| SCHEMBL2398615 | 0.70 | SLC6A3 (0.39) | CA2CA1CA9CA6CA12 | |
| Hydrochloric Acid SCHEMBL3517386 | 0.69 | CA1 (0.49) | CA2CA1CA9CA6CA12 | |
| Methane SCHEMBL28850761 | 0.69 | CA2 (0.49) | CA2CA1CA9CA6CA12 | |
| SCHEMBL3559017 | 0.68 | MAOA (0.42) | CA2CA1CA9CA12CA4 | |
| SCHEMBL27281101 | 0.67 | CA2 (0.47) | CA2CA1CA9CA6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613313-A1 | 2-PHENYL-BENZIMIDAZOL AND 2-PHENYL-IMIDAZO-4,5!-PYRIDINE DERIVATIVES AS CHECKPOINT KINASE CDS1 (CHK2) INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004093873-A1 | 2-PHENYL-BENZIMIDAZOL AND 2-PHENYL-IMIDAZO-`4,5!-PYRIDINE DERIVATIVES AS CHECKPOINT KINASE CDS1 (CHK2) INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-11-04 | — | — | WO | disclosed |