Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824333 | 0.97 | TSHR (0.39) | TSHRADRB2ADRB1ADRB3L3MBTL1 | |
| SCHEMBL5680406 | 0.90 | ADRB2 (0.37) | TSHRADRB2ADRB1ADRB3L3MBTL1 | |
| SCHEMBL5682285 | 0.85 | ALDH1A1 (0.41) | ADRB2ADRB1ADRB3L3MBTL1BCHE | |
| SCHEMBL13065489 | 0.81 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3293698 | 0.81 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL14364291 | 0.81 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL3293695 | 0.81 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL14377586 | 0.81 | ALDH1A1 (0.47) | TSHRMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6295192 | 0.79 | UPP1 (0.44) | TSHRMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL5677684 | 0.77 | L3MBTL1 (0.39) | TSHRADRB2ADRB1ADRB3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891036-B2 | Process for the preparation of ribofuranose derivatives | INALCO S.P.A. (IT) | 2005-05-10 | — | — | US | claimed |
| US-20040158059-A1 | Process for the preparation of ribofuranose derivatives | INALCO S.P.A. (IT) | 2004-08-12 | — | — | US | claimed |
| EP-1631573-A1 | PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES | INALCO SpA (IT) | 2006-03-08 | — | — | EP | disclosed |
| US-6891036-B2 | Process for the preparation of ribofuranose derivatives | INALCO S.P.A. (IT) | 2005-05-10 | — | — | US | disclosed |
| WO-2004069851-A1 | PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES | INALCO S.P.A. (IT) | 2004-08-19 | — | — | WO | disclosed |
| US-20040158059-A1 | Process for the preparation of ribofuranose derivatives | INALCO S.P.A. (IT) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158059-A1 | Process for the preparation of ribofuranose derivatives | RNGTT, RPIA, MRM1 | TSHR 3367/4885ADRB2 4776/4885ADRB1 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.