Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679149 | 0.92 | CCR2 (0.54) | CCR2ABCB11 | |
| SCHEMBL5682947 | 0.85 | CCR2 (0.57) | CCR2ABCB11 | |
| SCHEMBL5679091 | 0.85 | CCR2 (0.75) | CCR2ABCB11 | |
| SCHEMBL5683030 | 0.82 | CCR2 (0.53) | CCR2ABCB11 | |
| SCHEMBL5681505 | 0.82 | CCR2 (0.53) | CCR2ABCB11 | |
| SCHEMBL5680853 | 0.81 | CCR2 (0.51) | CCR2ABCB11 | |
| SCHEMBL7072404 | 0.78 | CCR2 (0.67) | CCR2ABCB11 | |
| SCHEMBL5679203 | 0.78 | CCR2 (0.45) | CCR2ABCB11 | |
| SCHEMBL7079549 | 0.78 | ABCB11 (0.54) | CCR2ABCB11 | |
| SCHEMBL7076054 | 0.77 | ABCB11 (0.67) | CCR2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268423-B1 | INDOLE DERIVATIVES AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2006-03-01 | — | — | EP | claimed |