SCHEMBL5685173

SCHEMBL5685173

CCOC(=O)C(C)Cc1ccc(O)c(OC)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 2/20 0.63
FOS P01100 1/20 0.63
TTR P02766 1/20 0.63
JUN P05412 1/20 0.63
NR3C1 P04150 1/20 0.63
HSD17B1 P14061 1/20 0.63
ALOX15 P16050 2/20 0.58
ALOX12 P18054 2/20 0.58
MMP1 P03956 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALDH1A1 P00352 2/20 0.54
GAA P10253 2/20 0.54
TSHR P16473 2/20 0.54
NFKB1 P19838 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
ALOX5 P09917 1/20 0.50
OR51E2 Q9H255 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4342540 0.89 ALOX15 (0.63) HSD17B2FOSTTRJUNNR3C1
SCHEMBL490769 0.87 HSD17B2 (0.60) HSD17B2FOSTTRJUNNR3C1
SCHEMBL5685443 0.86 HSD17B2 (0.59) HSD17B2FOSTTRJUNNR3C1
SCHEMBL5382445 0.84 HSD17B2 (0.57) HSD17B2FOSTTRJUNNR3C1
SCHEMBL12775014 0.84 FOS (0.65) HSD17B2FOSTTRJUNNR3C1
SCHEMBL3369599 0.84 HSD17B2 (0.57) HSD17B2FOSTTRJUNNR3C1
SCHEMBL22108693 0.84 FOS (0.69) HSD17B2FOSTTRJUNNR3C1
SCHEMBL30417396 0.84 FOS (0.69) HSD17B2FOSTTRJUNNR3C1
SCHEMBL3175155 0.84 FOS (0.69) HSD17B2FOSTTRJUNNR3C1
SCHEMBL12775269 0.84 FOS (0.69) HSD17B2FOSTTRJUNNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122065-A1 Amide compound and method of controlling plant disease with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed
EP-1577290-A1 AMIDE COMPOUND AND METHOD OF CONTROLLING PLANT DISEASE WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2005-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122065-A1 Amide compound and method of controlling plant disease with the same CBR3, C5, CLN6 HSD17B2 2438/4885FOS 3689/4885TTR 3029/4885
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 HSD17B2 2836/4885FOS 4320/4885TTR 2932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.