Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714715 | 0.76 | RAB9A (0.36) | NPC1PKMRAB9A | |
| SCHEMBL29714449 | 0.68 | NPC1 (0.35) | NPC1RAB9APOLBPTGDR2 | |
| SCHEMBL5188476 | 0.68 | RAB9A (0.40) | NPC1PKMRAB9APOLB | |
| SCHEMBL31075128 | 0.67 | ALDH1A1 (0.32) | NPC1RAB9A | |
| SCHEMBL38665543 | 0.66 | RAB9A (0.40) | NPC1PKMRAB9APOLB | |
| SCHEMBL28815019 | 0.66 | SMN1; SMN2 (0.46) | NPC1RAB9APTGDR2 | |
| SCHEMBL28463245 | 0.66 | PNMT (0.51) | NPC1PKMRAB9A | |
| SCHEMBL26105549 | 0.65 | ESR1 (0.47) | NPC1RAB9APOLB | |
| SCHEMBL29004324 | 0.65 | CD274 (0.48) | PTGDR2 | |
| SCHEMBL7860715 | 0.64 | KMT2A (0.42) | NPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132506-B2 | Peptide having osteogenetic activity and osteogenetic accelerator containing the same | KYOCERA CORPORATION (JP) | 2006-11-07 | — | — | US | disclosed |
| EP-1288228-B1 | BMP-2-derived peptides having osteogenetic activity and osteogenetic accelerator containing the same | NISHIMURA YOSHIHIKO (JP) | 2006-05-17 | — | — | EP | disclosed |
| US-20030082784-A1 | Novel peptide having osteogenetic activity and osteogenetic accelerator containing the same | YOSHIHIKO NISHIMURA | 2003-05-01 | — | — | US | disclosed |
| EP-1288228-A1 | BMP-2-derived peptides having osteogenetic activity and osteogenetic accelerator containing the same | Nishimura, Yoshihiko (JP) | 2003-03-05 | — | — | EP | disclosed |