Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830397 | 0.78 | PNMT (0.57) | RAB9ANPC1PNMTALDH1A1MAPT | |
| SCHEMBL26105549 | 0.77 | ESR1 (0.47) | RAB9ANPC1PNMTALDH1A1HPGD | |
| SCHEMBL9853832 | 0.76 | PNMT (0.42) | RAB9ANPC1PKMPNMTALDH1A1 | |
| SCHEMBL7699409 | 0.75 | PNMT (0.54) | RAB9ANPC1PNMTALDH1A1MAPT | |
| SCHEMBL60475 | 0.73 | FABP5 (0.45) | RAB9AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL14975286 | 0.73 | PNMT (0.51) | RAB9ANPC1PNMTALDH1A1MAPT | |
| SCHEMBL14714715 | 0.73 | RAB9A (0.36) | RAB9ANPC1PKMPNMTALDH1A1 | |
| SCHEMBL8473288 | 0.73 | PNMT (0.54) | RAB9ANPC1PNMTALDH1A1MAPT | |
| SCHEMBL8473291 | 0.73 | PNMT (0.54) | RAB9ANPC1PNMTALDH1A1MAPT | |
| SCHEMBL7860715 | 0.72 | KMT2A (0.42) | RAB9ANPC1PKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | THE PROCTER & GAMBLE COMPANY | 2007-06-07 | — | — | US | disclosed |
| WO-2007064762-A2 | CONJUGATES OF AMINO ACIDS AND VITAMIN B3 FOR PERCUTANEOUS DELIVERY OF VITAMIN B3 | THE PROCTER & GAMBLE COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |
| EP-1792630-A1 | Conjugates of amino acids and vitamin B3 for percutaneous delivery of vitamin B3 | The Procter & Gamble Company (US) | 2007-06-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070128145-A1 | Amino acid adducts for percutaneous delivery of vitamin B3 | SLC1A5, SLC19A1, PLPBP | RAB9A 2702/4885NPC1 1311/4885PKM 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.