Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23422579 | 1.00 | KHK (0.48) | KHKDPP4NAMPTADRB1HRH4 | |
| SCHEMBL23422596 | 1.00 | KHK (0.48) | KHKDPP4NAMPTADRB1HRH4 | |
| SCHEMBL8724123 | 0.88 | ADRB1 (0.53) | DPP4ADRB1GPR119MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL5180146 | 0.86 | ADRB1 (0.52) | DPP4ADRB1GPR119MAPTNPSR1 | |
| SCHEMBL25016623 | 0.82 | ADRB1 (0.47) | DPP4ADRB1GPR119MAPTNPSR1 | |
| SCHEMBL25016051 | 0.82 | ADRB1 (0.47) | DPP4ADRB1GPR119MAPTNPSR1 | |
| SCHEMBL5392075 | 0.82 | MAPT (0.48) | KHKNAMPTHRH4CCNCCDK8 | |
| SCHEMBL25017026 | 0.82 | ADRB1 (0.47) | DPP4ADRB1GPR119MAPTNPSR1 | |
| SCHEMBL21460260 | 0.81 | NAMPT (0.46) | KHKNAMPTHRH4CCNCCDK8 | |
| Hydrochloric Acid SCHEMBL5383104 | 0.81 | MAPT (0.52) | KHKNAMPTHRH4CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523292-B1 | HETEROARYL COMPOUNDS AND THEIR USE AS MER INHIBITORS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2021-12-15 | — | — | EP | disclosed |
| EP-2712863-B1 | Novel inhibitors of bacterial biofilms and related methods | SEQUOIA SCIENCES INC (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | SEQUOIA SCIENCES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | SEQUOIA SCIENCES, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-8324264-B1 | Inhibitors of bacterial biofilms and related methods | SEQUOIA SCIENCES, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1434485-B1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES FOR USE AS PESTICIDES | MERIAL LTD (US) | 2007-05-16 | — | — | EP | disclosed |
| US-20060270847-A1 | Process for producing nitrogenous heterocyclic compound | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-11-30 | — | — | US | disclosed |
| EP-1640364-A1 | PROCESS FOR PRODUCING NITROGENOUS HETEROCYCLIC COMPOUND | Toray Fine Chemicals Co., Ltd. (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274256-A1 | NOVEL INHIBITORS OF BACTERIAL BIOFILMS AND RELATED METHODS | BLVRB, MMP8, PGLS | KHK 2252/4885DPP4 2761/4885NAMPT 491/4885 |
| US-20060270847-A1 | Process for producing nitrogenous heterocyclic compound | HNMT, HRH4, QDPR | KHK 1539/4885DPP4 1210/4885NAMPT 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.