Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569245 | 0.83 | KMT2A (0.41) | ALDH1A1HTTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL569928 | 0.82 | LRRK2 (0.38) | NPSR1KDM4ESMN1; SMN2KMT2AHPGD | |
| SCHEMBL569786 | 0.81 | HCAR2 (0.48) | ALDH1A1CYP2C9CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL569400 | 0.81 | HTT (0.38) | ALDH1A1HTTCYP2C9CYP2C19TDP1 | |
| SCHEMBL569395 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HTTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL10182329 | 0.76 | CFTR (0.40) | ALDH1A1HTTNPSR1CYP1A2CYP2C9 | |
| SCHEMBL569756 | 0.76 | DRD3 (0.54) | ALDH1A1HTTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL569408 | 0.75 | MAPT (0.42) | ALDH1A1HTTTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL569511 | 0.73 | MAPT (0.47) | ALDH1A1NPSR1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10083554 | 0.72 | KMT2A (0.44) | ALDH1A1KMT2AMAPTHSD17B10LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |