Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569245 | 0.84 | KMT2A (0.41) | POLBMEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL569400 | 0.83 | HTT (0.38) | HDAC8MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL569928 | 0.81 | LRRK2 (0.38) | HDAC8MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL569396 | 0.81 | ALDH1A1 (0.38) | POLBHDAC8MEN1KMT2ACYP2C9 | |
| SCHEMBL569785 | 0.79 | HDAC8 (0.42) | HDAC8MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL569756 | 0.77 | DRD3 (0.54) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10182249 | 0.76 | JAK2 (0.46) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL10182396 | 0.76 | CFTR (0.44) | POLBHDAC8MEN1KMT2ACYP2C9 | |
| SCHEMBL569408 | 0.76 | MAPT (0.42) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10083554 | 0.75 | KMT2A (0.44) | POLBKMT2AMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |