Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 2/20 | 0.43 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658275 | 0.85 | HAO2 (0.54) | PIN1HAO2KMOHCAR2 | |
| SCHEMBL570062 | 0.83 | PIN1 (0.47) | PIN1HAO2HCAR2 | |
| SCHEMBL2198685 | 0.83 | IKBKB (0.43) | PIN1HAO2HCAR2 | |
| SCHEMBL16197762 | 0.82 | ALPL (0.46) | TYMPPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14152277 | 0.80 | PIN1 (0.58) | PIN1HAO2 | |
| SCHEMBL16883789 | 0.75 | ALK (0.48) | KMOHCAR2 | |
| SCHEMBL4885520 | 0.74 | PRKAB2 (0.43) | KMOPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4740858 | 0.73 | PRKAB2 (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4964605 | 0.73 | HAO2 (0.53) | HAO2HCAR2 | |
| SCHEMBL13539292 | 0.72 | SMN1; SMN2 (0.50) | PIN1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |