Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 13/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 13/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 13/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 13/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 13/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 13/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 13/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872475 | 0.85 | ALPL (0.49) | ALPL | |
| SCHEMBL16197762 | 0.84 | ALPL (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4740858 | 0.82 | PRKAB2 (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL569461 | 0.74 | PIN1 (0.56) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4964605 | 0.73 | HAO2 (0.53) | CA12ALPLHCAR2 | |
| SCHEMBL5011760 | 0.72 | FYN (0.42) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL570062 | 0.71 | PIN1 (0.47) | ALPLHCAR2 | |
| SCHEMBL7646423 | 0.69 | HAO2 (0.49) | CA12ALPL | |
| SCHEMBL5011757 | 0.68 | ALOX15 (0.54) | — | |
| SCHEMBL27658275 | 0.68 | HAO2 (0.54) | HCAR2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008062480-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF RIMONABANT | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-05-29 | — | — | WO | claimed |