SCHEMBL5697133

SCHEMBL5697133

CCO[SiH2]c1nncc(C2CCCCC2)c1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.31
TDO2 P48775 1/20 0.30
CACNA2D1 P54289 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4058977 0.66 TDO2 (0.33) TDO2
SCHEMBL4058269 0.63 TDO2 (0.35) TDO2
SCHEMBL24713155 0.63 PDE10A (0.36) PDE10ATDO2
SCHEMBL3101449 0.60 TDO2 (0.38) TDO2
SCHEMBL9350412 0.60 TDO2 (0.38) TDO2
SCHEMBL10456696 0.60 FFAR2 (0.34) TDO2CACNA2D1
SCHEMBL26045412 0.59 ALDH1A1 (0.44)
SCHEMBL27542494 0.59 TDO2 (0.44) PDE10ATDO2
SCHEMBL28948825 0.57 TDO2 (0.39) TDO2
SCHEMBL18508459 0.56 L3MBTL1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed