Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930124 | 0.81 | TSHR (0.40) | TSHRMETAP1CYP2D6LMNASPHK1 | |
| SCHEMBL22746311 | 0.75 | — | — | |
| SCHEMBL12583427 | 0.74 | TSHR (0.38) | TSHRCYP2D6POLBOPRM1ALDH1A1 | |
| SCHEMBL276383 | 0.74 | TSHR (0.38) | TSHRCYP2D6POLBOPRM1ALDH1A1 | |
| SCHEMBL16349710 | 0.73 | SPHK1 (0.34) | TSHRMETAP1SPHK1POLBOPRM1 | |
| Hydrochloric Acid SCHEMBL22575465 | 0.72 | TSHR (0.36) | TSHRCYP2D6POLBALDH1A1HPGD | |
| SCHEMBL22641806 | 0.71 | OPRM1 (0.33) | METAP1OPRM1 | |
| SCHEMBL20434141 | 0.71 | OPRM1 (0.33) | TSHRMETAP1TP53CYP3A4OPRM1 | |
| SCHEMBL4233707 | 0.71 | — | — | |
| SCHEMBL7571426 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507511-B1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2006-07-26 | — | — | EP | disclosed |
| EP-1507511-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2005-02-23 | — | — | EP | disclosed |
| EP-1507512-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2005-02-23 | — | — | EP | disclosed |
| US-20040241131-A1 | Compositions containing malonate salts in preventing in-grown hair arising from shaving | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-12-02 | — | — | US | disclosed |
| US-20030228337-A1 | Personal care compositions with hydroxy amine neutralized polymers | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-11 | — | — | US | disclosed |
| WO-2003099252-A1 | COSMETIC COMPOSITIONS WITH HYDROXY AMINE SALTS OF MALONIC ACID | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| WO-2003099253-A1 | PERSONAL CARE COMPOSITIONS WITH HYDROXY AMINE NEUTRALIZED POLYMERS | UNILEVER PLC (GB) | 2003-12-04 | — | — | WO | disclosed |
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224023-A1 | Cosmetic compositions with hydroxy amine salts of malonic acid | CUTA, TYR, DDC | TSHR 3448/4885METAP1 1140/4885CYP2D6 1165/4885 |
| US-20030228337-A1 | Personal care compositions with hydroxy amine neutralized polymers | CUTA, PARN, POLH | TSHR 3835/4885METAP1 776/4885CYP2D6 4115/4885 |
| US-20040241131-A1 | Compositions containing malonate salts in preventing in-grown hair arising from shaving | DPM1, POLR1C, MSH6 | TSHR 4651/4885METAP1 427/4885CYP2D6 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.