Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185273 | 0.80 | ALOX15 (0.44) | HCAR2KMT2A | |
| SCHEMBL15825699 | 0.73 | HCAR2 (0.58) | HCAR2 | |
| SCHEMBL12985499 | 0.73 | PDE4D (0.38) | HCAR2KMT2A | |
| SCHEMBL4631308 | 0.73 | HCAR2 (0.63) | HCAR2 | |
| SCHEMBL9912568 | 0.72 | ABCC8 (0.54) | HCAR2 | |
| SCHEMBL7234538 | 0.71 | HCAR2 (0.57) | HCAR2KMT2A | |
| SCHEMBL1829755 | 0.71 | L3MBTL1 (0.32) | KMT2A | |
| SCHEMBL12121211 | 0.70 | DYRK1A (0.46) | — | |
| SCHEMBL12263262 | 0.69 | HCAR2 (0.55) | HCAR2KMT2A | |
| SCHEMBL31741716 | 0.69 | HCAR2 (0.59) | HCAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016934-A2 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015002994-A2 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |