Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 12/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426313 | 0.80 | HCRTR2 (0.39) | HCRTR2HCRTR1MEN1KMT2ACCR5 | |
| Hydrochloric Acid SCHEMBL5431787 | 0.78 | MEN1 (0.48) | HCRTR2HCRTR1MEN1KMT2ACCR5 | |
| SCHEMBL5430005 | 0.75 | MEN1 (0.40) | HCRTR2HCRTR1MEN1KMT2ACCR5 | |
| SCHEMBL5430020 | 0.74 | MEN1 (0.44) | HCRTR2HCRTR1MEN1KMT2ARIPK1 | |
| SCHEMBL5423713 | 0.74 | USP30 (0.48) | HCRTR2HCRTR1MEN1KMT2ARIPK1 | |
| SCHEMBL5423453 | 0.74 | NR3C1 (0.39) | HCRTR2HCRTR1MEN1KMT2ARIPK1 | |
| SCHEMBL5425021 | 0.74 | NR3C1 (0.45) | KMT2ACYP3A4CYP2D6 | |
| SCHEMBL5427290 | 0.74 | LMNA (0.50) | MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL5422216 | 0.72 | RIPK1 (0.47) | HCRTR2HCRTR1MEN1KMT2ACCR5 | |
| SCHEMBL5429847 | 0.72 | LIPE (0.43) | HCRTR2HCRTR1MEN1KMT2ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1683797-A1 | HETEROCYCLIC SPIRO COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-26 | — | — | EP | disclosed |