Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360639 | 0.84 | ALDH1A1 (0.37) | TAS1R3TAS1R1TAS1R2ALDH1A1MAPT | |
| SCHEMBL5361238 | 0.84 | KEAP1 (0.44) | TAS1R3TAS1R1TAS1R2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9475356 | 0.83 | KEAP1 (0.43) | TAS1R3TAS1R1TAS1R2ALDH1A1MAPT | |
| SCHEMBL7038698 | 0.83 | CASP1 (0.39) | TAS1R3TAS1R1TAS1R2ALDH1A1MAPT | |
| SCHEMBL7038205 | 0.76 | KEAP1 (0.43) | TAS1R3TAS1R1TAS1R2CYP3A4ENPP2 | |
| SCHEMBL14408161 | 0.75 | STAT3 (0.36) | ALDH1A1MAPTSMN1; SMN2TP53HPGD | |
| SCHEMBL9821175 | 0.75 | CSNK2A2 (0.35) | ALDH1A1MAPTSMN1; SMN2MEN1HPGD | |
| SCHEMBL5704420 | 0.74 | KDM4E (0.40) | ALDH1A1MAPTMEN1TP53CYP3A4 | |
| SCHEMBL29078536 | 0.74 | TSHR (0.37) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL14408183 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MAPTSMN1; SMN2MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319656-B1 | A NEW PROCESS FOR PREPARING A QUINOLONE-CARBOXYLIC ACID | LYNCHEM CO LTD (CN) | 2006-08-23 | — | — | EP | disclosed |
| US-6699992-B2 | REACTING M-FLUOROACETOPHENONE COMPOUND WITH ALKYL CARBONATE; REACTING ESTER OBTAINED WITH ALKYL ORTHOFORMATE AND AMINE; CYCLIZATION IN BASE | LYNCHEM CO., LTD. (CN) | 2004-03-02 | — | — | US | disclosed |
| US-20030166936-A1 | Process for preparing a quinolone-carboxylic acid | LYNCHEM CO., LTD. (CN) | 2003-09-04 | — | — | US | disclosed |
| EP-1319656-A1 | A NEW PROCESS FOR PREPARING A QUINOLONE-CARBOXYLIC ACID | Lynchem Co., Ltd. (CN) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166936-A1 | Process for preparing a quinolone-carboxylic acid | CYP4B1, QPCT, NQO2 | TAS1R3 3436/4885TAS1R1 2550/4885TAS1R2 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.