Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361238 | 0.86 | KEAP1 (0.44) | ALDH1A1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL7038698 | 0.84 | CASP1 (0.39) | ALDH1A1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL5704378 | 0.84 | TAS1R3 (0.35) | ALDH1A1TAS1R3TAS1R1TAS1R2MEN1 | |
| Hydrochloric Acid SCHEMBL9475356 | 0.84 | KEAP1 (0.43) | ALDH1A1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL8038013 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPTHPGDSMN1; SMN2 | |
| SCHEMBL5362826 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALOX15TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7038205 | 0.77 | KEAP1 (0.43) | TAS1R3TAS1R1TAS1R2CYP3A4TRPV4 | |
| SCHEMBL8754934 | 0.75 | ALDH1A1 (0.43) | ALDH1A1ALOX15MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9790158 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL8048009 | 0.72 | ALDH1A1 (0.41) | ALDH1A1ALOX15MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114577940-A | Purity analysis method of 2, 4-dichloro-3-cyano-5-fluorobenzoyl chloride | 营口兴福化工有限公司 | 2022-06-03 | — | — | CN | claimed |
| US-7268248-B2 | Bichlorinated compounds formed under with carboxy groupand elimation of water | BAYER AKTIENGESELLSCHAFT (DE) | 2007-09-11 | — | — | US | claimed |
| US-20040167350-A1 | Bichlorinated compounds formed under with carboxy groupand elimation of water | MARHOLD ALBRECHT (DE) | 2004-08-26 | — | — | US | claimed |
| US-20030092929-A1 | Using halogenated xylene compound; chemical intermediate for quinolone antibiotics | MARHOLD ALBRECHT (DE) | 2003-05-15 | — | — | US | claimed |
| EP-0977729-B1 | 3-CYANO-2,4,5-TRIFLUORO-BENZOYL FLUORIDE AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BAYER AG (DE) | 2002-03-13 | — | — | EP | claimed |
| US-20010023300-A1 | Preparing by reacting 3-cyano-2,4-dichloro-4-fluoro-benzoyl chloride nucleophilically with a fluoridizing agent; forming 3-cyano-2,4,5-trifluoro-benzoyl chloride from title compound; intermediates to antiinfective quinolonecarboxylic acids | MARHOLD ALBRECHT (DE) | 2001-09-20 | — | — | US | claimed |
| US-6229040-B1 | USING FREE RADICAL CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | claimed |
| EP-0977729-A1 | 3-CYANO-2,4,5-TRIFLUORO-BENZOYL FLUORIDE AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BAYER AG (DE) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047862-A1 | 3-CYANO-2,4,5-TRIFLUORO-BENZOYL FLUORIDE AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-29 | — | — | WO | claimed |
| CN-111989314-B | Method for hydrolyzing quinolone formate | 拜耳动物保健有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| CN-114577940-A | Purity analysis method of 2, 4-dichloro-3-cyano-5-fluorobenzoyl chloride | 营口兴福化工有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114577940-A | Purity analysis method of 2, 4-dichloro-3-cyano-5-fluorobenzoyl chloride | 营口兴福化工有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114577940-A | Purity analysis method of 2, 4-dichloro-3-cyano-5-fluorobenzoyl chloride | 营口兴福化工有限公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-1998026779-A1 | THE USE OF 7-(2-OXA-5,8-DIAZABICYCLO[4.3.0]NON-8-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDON CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF HELICOBACTER PYLORI INFECTIONS AND ASSOCIATED GASTRODUODENAL DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998026768-A2 | USE OF 7-(1-AMINOMETHYL-2-OXA-7-AZA-BICYCLO[3.3.0]OCT-7-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDONE CARBOXYLIC ACID DERIVATIVES FOR TREATING HELICOBACTER PYLORI INFECTIONS AND THE GASTRODUODENAL DISEASES ASSOCIATED THEREWITH | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |
| US-5190955-A | Bactericides, effective against antibiotic resistant germs | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5051418-A | Antibacterial 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| US-4908366-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| EP-0276700-A1 | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1988-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167350-A1 | Bichlorinated compounds formed under with carboxy groupand elimation of water | CLIC4, AFF4, CBR1 | ALDH1A1 407/4885ALOX15 1016/4885TAS1R3 4317/4885 |
| US-20010023300-A1 | Preparing by reacting 3-cyano-2,4-dichloro-4-fluoro-benzoyl chloride nucleophilically with a fluoridizing agent; forming 3-cyano-2,4,5-trifluoro-benzoyl chloride from title compound; intermediates to antiinfective quinolonecarboxylic acids | CLIC4, AFF4, CBR1 | ALDH1A1 1360/4885ALOX15 768/4885TAS1R3 4735/4885 |
| US-20030092929-A1 | Using halogenated xylene compound; chemical intermediate for quinolone antibiotics | CLIC4, FLI1, AFF4 | ALDH1A1 1343/4885ALOX15 2100/4885TAS1R3 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.