Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982728 | 0.81 | P2RX7 (0.32) | ALDH1A1NPC1RAB9AHTTKMT2A | |
| SCHEMBL5707571 | 0.81 | P2RX7 (0.32) | ALDH1A1NPC1RAB9AHTTKMT2A | |
| SCHEMBL5707632 | 0.81 | P2RX7 (0.32) | ALDH1A1NPC1RAB9AHTTKMT2A | |
| SCHEMBL4750928 | 0.80 | SLC6A2 (0.31) | ALDH1A1HTT | |
| SCHEMBL6843109 | 0.78 | AR (0.44) | ALDH1A1GAANPC1MAPTKDM4E | |
| SCHEMBL8960840 | 0.77 | SLC6A2 (0.33) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL6842407 | 0.77 | SLC6A2 (0.33) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL5707587 | 0.77 | SLC6A2 (0.33) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL2907033 | 0.77 | SLC6A2 (0.33) | ALDH1A1NPC1RAB9AMAPTHTT | |
| SCHEMBL3395341 | 0.76 | HTT (0.33) | ALDH1A1NPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6764829-B2 | DETECTING PARASITES USING CHROMOGENIC SUBSTRATES; OBTAIN SAMPLE, INCUBATE WITH CHROMGENIC SUBSTRATE, DETECT FORMATION OF CHROMOPHORE PRODUCT | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2004-07-20 | — | — | US | disclosed |
| US-20020132263-A1 | Enzyme detection/assay method and substrates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-09-19 | — | — | US | disclosed |
| US-6379911-B2 | ANALYZING NUCLEOSIDE HYDROLASES; DETECTING PARASITES | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY | 2002-04-30 | — | — | US | disclosed |
| US-20010019823-A1 | ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010019823-A1 | ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES | PNP, TREH, XDH | ALDH1A1 2151/4885GAA 86/4885NPC1 3012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.