Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535978 | 0.77 | TSHR (0.47) | MEN1KMT2AMAPTTLR9NPC1 | |
| SCHEMBL5708797 | 0.76 | ALDH1A1 (0.48) | MEN1KMT2AMAPTTLR9NPC1 | |
| SCHEMBL5708902 | 0.72 | ALDH1A1 (0.62) | MEN1KMT2AMAPTTLR9NPC1 | |
| SCHEMBL12544826 | 0.71 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9814160 | 0.70 | SLC9A1 (0.42) | MEN1KMT2AMAPTTLR9NPC1 | |
| SCHEMBL8513944 | 0.70 | MAPT (0.55) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8611539 | 0.70 | SLC9A1 (0.64) | MEN1KMT2AMAPTNPC1ALDH1A1 | |
| SCHEMBL9461983 | 0.69 | GRIN2D (0.46) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL9814173 | 0.69 | SLC9A1 (0.44) | MEN1KMT2AMAPTTLR9NPC1 | |
| SCHEMBL8986411 | 0.69 | ATM (0.52) | MEN1KMT2AMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | claimed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | claimed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | claimed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | claimed |
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| EP-1399445-A2 | SUBSTITUTED PYRROLOQUINOLINES AND PYRIDOQUINOLINES AS SEROTONIN AGONISTS AND ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
| WO-2002059124-A2 | SUBSTITUTED PYRROLOQUINOLINES AND PYRIDOQUINOLINES AS SEROTONIN AGONISTS AND ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | MEN1 2811/4885KMT2A 686/4885MAPT 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.