Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648511 | 0.82 | GAA (0.76) | ALDH1A1CYP3A4TSHRALOX5GAA | |
| Metacetamol SCHEMBL181254 | 0.82 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4TSHRNLRP3 | |
| Metacetamol SCHEMBL31195432 | 0.82 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4TSHRNLRP3 | |
| SCHEMBL28032785 | 0.81 | CYP3A4 (0.60) | ALDH1A1CYP1A2CYP3A4TSHRALOX5 | |
| SCHEMBL26105067 | 0.80 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP3A4TSHRGAA | |
| SCHEMBL9525972 | 0.79 | GAA (0.54) | ALDH1A1CYP1A2ALOX5GAANLRP3 | |
| SCHEMBL27625271 | 0.79 | CYP3A4 (0.63) | ALDH1A1CYP3A4TSHRALOX5KMT2A | |
| SCHEMBL588131 | 0.79 | ALOX5 (1.00) | ALDH1A1CYP3A4TSHRALOX5GAA | |
| SCHEMBL425872 | 0.79 | ALOX5 (1.00) | ALDH1A1CYP3A4TSHRALOX5GAA | |
| SCHEMBL28010783 | 0.78 | MTNR1A (0.60) | ALDH1A1CYP3A4TSHRALOX5NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103622842-B | Delivery of particles | 宝洁公司 | 2017-10-27 | — | — | CN | disclosed |
| WO-2017109132-A1 | PROCESS USING A COMPOSITION COMPRISING A NEUTRALIZED FATTY ACID, AND A PARTICULAR CLAY | L'OREAL (FR) | 2017-06-29 | — | — | WO | disclosed |
| CN-102858944-B | Delivery of particles | 宝洁公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | ALDH1A1 87/4885CYP1A2 1003/4885CYP3A4 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.