Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360996 | 0.84 | RAB9A (0.69) | GAASMN1; SMN2ALDH1A1CYP1A2NLRP3 | |
| Hydrochloric Acid SCHEMBL30967923 | 0.81 | GAA (0.50) | GAASMN1; SMN2ALDH1A1ALOX5POLB | |
| SCHEMBL1531488 | 0.81 | ALOX5 (0.72) | GAASMN1; SMN2ALDH1A1ALOX5RAB9A | |
| SCHEMBL5708790 | 0.79 | ALDH1A1 (0.69) | GAASMN1; SMN2ALDH1A1CYP1A2NLRP3 | |
| SCHEMBL11434309 | 0.79 | ALDH1A1 (0.50) | GAAALDH1A1CYP1A2NLRP3MEN1 | |
| SCHEMBL19639788 | 0.79 | ALDH1A1 (0.57) | GAASMN1; SMN2ALDH1A1CYP1A2POLB | |
| SCHEMBL6907375 | 0.77 | ALDH1A1 (0.47) | GAAALDH1A1CYP1A2NLRP3POLB | |
| SCHEMBL6907370 | 0.77 | NLRP3 (0.56) | GAAALDH1A1CYP1A2NLRP3POLB | |
| SCHEMBL26105067 | 0.76 | ALDH1A1 (0.53) | GAASMN1; SMN2ALDH1A1CYP1A2RAB9A | |
| SCHEMBL11461935 | 0.74 | P2RX7 (0.61) | GAASMN1; SMN2ALDH1A1CYP1A2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-B1 | 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES | L'OREAL (FR) | 1993-07-14 | — | — | EP | disclosed |
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |